伐昔洛韦 - CAS:124832-26-4 - CAS号查询_生物试剂_化学试剂_分析试剂_实验试剂-普西唐试剂商城

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中文名称:	伐昔洛韦一键复制产品信息
英文名称:	Valacyclovir
别名:	万乃洛韦 Valaciclovir
CAS No:	124832-26-4	分子式:	C₁₃H₂₀N₆O₄	分子量:	324.34
CAS No:	124832-26-4
分子式:	C₁₃H₂₀N₆O₄
分子量:	324.34

安全技术说明书(PDF) MSDS(PDF) 点击下载产品说明书(PDF)

V10092 伐昔洛韦 ≥98% (普西唐-psaitong)

相关产品

包装规格：

10mg 50mg 250mg in glass bottle

产品描述：

基本信息

产品编号：V10092
产品名称：Valacyclovir
CAS:	124832-26-4	储存条件	粉末	-20℃	四年
分子式：	C13H20N6O4
分子量	324.34
化学名：	2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate
Solubility (25°C)	体外	DMSO
		Ethanol
		Water
	体内	现配现用
＜1mg/ml表示微溶或不溶。
普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

生物活性

产品描述	一种口服有效的抗病毒药物，可以抑制单纯疱疹，带状疱疹和疱疹 B。
靶点/IC₅₀	HSV-1 2.9μg/mL (IC50)
体外研究	Valacyclovir (Valaciclovir; VACV) uptake was concentration dependent and saturable with a Michaelis-Menten constant and maximum velocity of 1.64mM and 23.34nmol/mg protein/5 min, respectively. A very similar Km value was obtained in hPEPT1/CHO cells and in rat and rabbit tissues and Caco-2 cells, suggesting that hPEPT1 dominates the intestinal transport properties of VACV in vitro.
体内研究	For treatment of a first episode of genital herpes, a large comparative trial has shown that Valacyclovir (1g twice a day) is as effective as acyclovir (200mg five times a day) when given for 10 days. For treating recurrences, two trials show that valacyclovir is as effective as acyclovir (200mg five times a day) with a treatment period of 5 days. A daily dose of 1g of valacyclovir is as effective as 2g daily. Valacyclovir can be administered once a day. The concentrations of acyclovir in serum and CSF were measured at steady state after 6days of oral treatment with 1,000mg of valacyclovir three times a day. EC50 values of PE and AC in 3T3 cells were 0.02 and 0.01ug/ml, while values in BHK cells were 0.2 and 0.03ug/ml. Treatment of infected immunosuppressed mice and FA and VA (b.i.d., 5.5days) reduced the proportion with erythema from 100% to 24% and 38%, and eliminated ear paralysis, ear lesions (vesicles, etc) and death. Virus was absent from ear and brainstem by day 6, but reappeared after discontinuation in mice treated with VA.

保存条件：

-20℃

UN码：

HazardClass：

危害声明：

安全说明：

搜索质检报告(COA)

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

质量 =

浓度 *

体积 *

分子量

*选择对应的单位 *空出希望得到的变量，填写另外两个变量

用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入输出 )

* = *

连续稀释计算器方程

连续稀释
初始浓度:
稀释倍数:

计算结果

C1=C0/X	C1:		LOG(C1):
C2=C1/X	C2:		LOG(C2):
C3=C2/X	C3:		LOG(C3):
C4=C3/X	C4:		LOG(C4):
C5=C4/X	C5:		LOG(C5):
C6=C5/X	C6:		LOG(C6):
C7=C6/X	C7:		LOG(C7):
C8=C7/X	C8:		LOG(C8):

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