中文名称: 托泊地芬  一键复制产品信息
英文名称: Tropodifene
CAS No: 15790-02-0
分子式: C25H29NO4
分子量: 407.5
T10844 托泊地芬 (普西唐-psaitong)
包装规格:
25mg 50mg 100mg in glass bottle
产品描述:

基本信息

产品编号:

T10844

产品名称:

Tropodifene

CAS:

15790-02-0

 

储存条件

粉末

-20℃

四年

分子式:

C25H29NO4

溶于液体

-80℃

二年

分子量

407.50

  

 

化学名: 

3-(p-Acetyloxyphenyl)-2-phenylpropionic acid (1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3alpha-yl ester

Solubility (25°C):

 

体外:

 

DMSO

 

Ethanol

 

Water

 

体内(现配现用):

 

1mg/ml表示微溶或不溶。

普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。

 

生物活性

产品描述

一种α-肾上腺素能受体 (α-Adrenergic receptor) 抑制剂。

靶点

α-Adrenergic

体内研究

Tropaphen has a beneficial effect on hypertension.The therapeutic effect of this preparation is more constant in diseases accompanied by spasm of the peripheral vessels.Tropaphen has a very marked adrenolytic and vasodilator action.It greatly lowers the tone of the peripheral vessels.The preparation is effective starting with a dose of 0.1mg/kg.After injection of the drug in a dose of 0.25mg/kg,a considerable and gradually progressive decrease in the perfusion pressure takes place.The pressure falls by 30-35% and remained at a low level for 90-100 min.With a dose of tropaphen of 0.5mg/kg,the perfusion pressure falls by 40-45% and remains low for 120 min or more.Strong vasodilatation is also observed after injection of tropaphen into intact rabbits.

 

推荐实验方法(仅供参考)

动物实验:

 

Rabbits

The drug is injected intravenously into rabbits.Experiments on the isolated ears of the rabbits are carried out by the Kravkov--Pisemskii method.The effect of tropaphen on the ear vessels of the intact rabbit is judged by the changes in the temperature of the ear.The temperature is measured by means of an electrothermometer,the detector of which is fixed to the internal surface of the ear.The dilation of the auricular vessels is also examined under the microscope,observations being made on the lumen of the marginal artery and vein.

保存条件:
-20℃
UN码:
HazardClass:
危害声明:
安全说明:
搜索质检报告(COA)

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • =
    *
    *
    *选择对应的单位 *空出希望得到的变量,填写另外两个变量

用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )

  • * = *

连续稀释计算器方程

  • 连续稀释

  • 初始浓度:
  • 稀释倍数:
  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):