| 中文名称: | CIBA 2330Go | ||||
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| 英文名称: | Nitroxazepine | ||||
| 别名: | 5-[3-(dimethylamino)propyl]-8-nitro-benzo[b][1,4]benzoxazepin-6-one | ||||
| CAS No: | 47439-36-1 | 分子式: | C18H19N3O4 | 分子量: | 341.36 |
| CAS No: | 47439-36-1 | ||||
| 分子式: | C18H19N3O4 | ||||
| 分子量: | 341.36 | ||||
基本信息
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产品编号： |
N11398 |
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产品名称： |
Nitroxazepine |
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CAS: |
47439-36-1 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式： |
溶于液体 |
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分子量 |
341.36 |
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化学名： |
5-[3-(dimethylamino)propyl]-8-nitro-benzo[b][1,4]benzoxazepin-6-one |
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Solubility (25°C)： |
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体外:
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DMSO |
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Ethanol |
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Water |
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体内(现配现用): |
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＜1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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生物活性
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产品描述 |
一种三环抗抑郁化合物 (TCA)，可用于抗抑郁的研究。Nitroxazepin 作为 5-羟色胺去甲肾上腺素再摄取抑制剂。 |
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靶点 |
serotonin-norepinephrine reuptake |
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体外研究 |
The in vitro effect of Nitroxazepine (Sintamil), as a modulator alone and in combination with hydroxyurea (HU), on cytotoxicity is studied in 16 cases of human chronic myeloid leukemia (CML). The cytotoxicity of the drugs as a function of the exposure dose (HU, 100μM; Nitroxazepine, 10μg/mL) and the exposure time (1 h) to the agent is investigated. Cytotoxicity is evaluated as the inhibition of incorporation of [3H-methyl]thymidine in the nucleic acids of CML cells. Cytotoxicity of HU is greatly enhanced (P<0.001) by 1 h exposure of the CML cells to Nitroxazepine. The present data indicate that Nitroxazepine potentiates the cytotoxic activity of HU in CML cells[1]. Nitroxazepine is indicated for the treatment of nocturnal enuresis. Nitroxazepine has similar effects to imipramine, but with certain advantages, such as lower anticholinergic side effects. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
