产品简介：
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a tetramer of 36 kDa subunits, is a catalytic enzyme involved in glycolysis. GAPDH catalyzes the reversible reduction of glyceraldehyde-3-phosphate to 3-phosphoglycerol phosphate in the presence of NAD+. Besides functioning as a glycolytic enzyme in the cytoplasm, mammalian GAPDH is also involved in a variety of intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. Glyceraldehyde-3-phosphate dehydrogenase was also found to bind to mutant polyglutamine proteins formed in neurodegenerative diseases such as Huntington′s disease, to bind to the cytoplasmic domain of APP (amyloid precursor protein), and to bind and protect telomeres from chemotherapy-induced rapid degradation. GAPDH has also been suggested as a promising drug target for hepatocellular carcinoma therapy, but has also been shown to have apoptotic activity by its binding to the E3 ubiquitin ligase Siah1。
.
来源：
Recombinant Expression
酶活定义：
One unit Glycerol-3-dehydrogenase will reduce 1 µmol of NAD in one minute at 37℃ and pH 8.0, generate 1 µmol of NADH.
保存条件：
-20℃
UN码：
HazardClass：
危害声明：
安全说明：
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
