| 中文名称: | GW5074 | ||||
|---|---|---|---|---|---|
| 英文名称: | GW5074 | ||||
| 别名: | 3' ,4' ,5' ,6'-四羟基-3H-螺[异苯并呋喃-1,9'-氧杂蒽]-3-酮 3',4',5',6'-Tetrahydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one | ||||
| CAS No: | 220904-83-6 | 分子式: | C15H8Br2InO2 | 分子量: | 520.94 |
| CAS No: | 220904-83-6 | ||||
| 分子式: | C15H8Br2InO2 | ||||
| 分子量: | 520.94 | ||||
| MDL: | MFCD03453076 | ||||
![N1-(4-氯苯基)-6-甲基-N5-[3-(9H-嘌呤-6-基)-2-吡啶]-1,5-异喹啉二胺](http:///www.jm-bio.com/content/xtheme/beijingjinming/images/noimage.jpg)
一种C-RAF-1激酶抑制剂和PMA介导的ERK1／2活化剂，IC50：9nM。
GW 5074 is a Raf-1 kinase inhibitor. The compound has been used in research studying the Ras/Raf-1/ERK pathway in human airway epithelial cells A549 and has demonstrated the ability to inhibit PMA-mediated activation of ERK1/2. In the presence of GW 5074, YC-1 induced p44/42 MAPK activation is weakened in A549 cells. GW 5074 has been shown to block low potassium (LK) induced cell death and prevent neurodegeneration。
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
