| 中文名称: | 法倔唑 | ||||
|---|---|---|---|---|---|
| 英文名称: | Fadrozole | ||||
| 别名: | 法倔唑 CGS 16949A free base; (Rac)-FAD286 | ||||
| CAS No: | 102676-47-1 | 分子式: | C14H13N3 | 分子量: | 223.11095 |
| CAS No: | 102676-47-1 | ||||
| 分子式: | C14H13N3 | ||||
| 分子量: | 223.11095 | ||||
一种有效，选择性和非甾体类的 aromatase 抑制剂，IC50 值为6.4 nM。
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity. Fadrozole specifically inhibits aromatase, blocking the aromatization of androstenedione and testosterone into estrone and estradiol, respectively, the final step in estrogen biosynthesis; the reduction in estrogen levels may inhibit growth in estrogen-dependent cancers. Aromatase, a member of the cytochrome P-450 superfamily, is found in many tissues; overexpression has been linked to the development of preneoplastic and neoplastic changes in breast tissue. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
