| 中文名称: | CREBtide 一键复制产品信息 | ||||
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| 英文名称: | CREBtide | ||||
| 别名: | CREBtide Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg | ||||
| CAS No: | 149155-45-3 | 分子式: | C73H129N29O19 | 分子量: | 1716.99 |
| CAS No: | 149155-45-3 | ||||
| 分子式: | C73H129N29O19 | ||||
| 分子量: | 1716.99 | ||||
基本信息
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产品编号： |
C11394 |
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产品名称： |
CREBtide |
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CAS: |
149155-45-3 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式： |
溶于液体 |
-80℃ |
两年 |
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分子量 |
1716.99 |
-20℃ |
一个月 |
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化学名： |
Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg |
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Solubility (25°C)： |
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体外:
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DMSO |
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Ethanol |
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Water |
100mg/mL(58.24mM;Need ultrasonic) |
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体内(现配现用): |
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＜1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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制备储备液
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浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
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1mM |
0.5824mL |
2.9121mL |
5.8241mL |
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5mM |
0.1165mL |
0.5824mL |
1.1648mL |
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10mM |
0.0582mL |
0.2912mL |
0.5824mL |
生物活性
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产品描述 |
一种合成的含 13 个氨基酸的肽，作为一种 PKA 底物。 |
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靶点 |
PKA |
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体外研究 |
delta-CREB is a spliced variant of cAMP response element binding protein (CREB). CREBtide (KRREILSRRPSYR), a synthetic peptide based on the phosphorylation sequence in delta-CREB. delta-CREB and CREBtide are tested as substrates of cAMPdependent protein kinase (cAK). The apparent Km of CREBtide phosphorylation by cAK is 3.9μM, which is 10-fold lower than that of Kemptide (Km=39μM), the synthetic peptide substrate most often employed for cAK measurement. The Vmax values are 12.4mumol/(min.mg) for CREBtide and 9.8mumol/(min.mg) for Kemptide. The apparent Km of CREBtide phosphorylation by cGMP-dependent protein kinase (cGK) is 2.9μM and the Vmax value is 3.2mumol/(min.mg). Both deltaCREB and CREBtide are phosphorylated at a much slower rate by cGK as compared with cAK, implying that the high cAK/cGK specificity exhibits by delta-CREB is retained by the peptide. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
