乙酰辅酶A钠盐 - CAS:102029-73-2 - CAS号查询_生物试剂_化学试剂_分析试剂

中文名称:	乙酰辅酶A钠盐促销一键复制产品信息
英文名称:	Acetyl coenzyme A sodium salt
别名:	乙酰辅酶A钠盐 Acetyl-CoA
CAS No:	102029-73-2	分子式:	C₂₃H₃₅N₇Na₃O₁₇P₃S	分子量:	875.52
CAS No:	102029-73-2
分子式:	C₂₃H₃₅N₇Na₃O₁₇P₃S
分子量:	875.52

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A12448 乙酰辅酶A钠盐 ≥95% (普西唐-psaitong)

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包装规格：

5mg 10mg in glass bottle

溶解性：

溶于水(100mg/mL）

产品描述：

基本信息

产品编号：	A12448
产品名称：	Acetyl coenzyme A sodium salt
CAS:	102029-73-2	储存条件	粉末	-20℃	四年

分子式：	C23H35N7Na3O17P3S		溶于液体	-80℃	六个月
分子量	875.52			-20℃	一个月
化学名：	Coenzyme A, S-acetate, trisodium salt (9CI)
Solubility (25°C)：
体外:	DMSO	<1mg/mL(insoluble or slightly soluble)
	Ethanol
	Water	80mg/mL (91.3743mM; Need ultrasonic)
体内(现配现用):
＜1mg/ml表示微溶或不溶。
普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

制备储备液

浓度溶液体积质量	1mg	5mg	10mg
1mM	1.1422mL	5.7109mL	11.4218mL
5mM	0.2284mL	1.1422mL	2.2844mL
10mM	0.1142mL	0.5711mL	1.1422mL

生物活性

产品描述

一种重要的代谢中间产物。Acetyl Coenzyme A trisodium 是糖酵解丙酮酸进入三羧酸 (TCA) 循环的实际分子，是脂质合成的关键前体，并且是乙酰基乙酰化的唯一供体，还是一种丙酮酸羧化酶 (PC) 的有效变构活化剂。

体外研究

Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant molecule constituted by an acetyl moiety (CH3CO) linked to coenzyme A (CoA), a derivative of vitamin B5 and cysteine, through a thioester bond. As thioester bonds are energy rich, the chemical structure of acetyl-CoA facilitates the transfer of the acetyl moiety to a variety of acceptor molecules, including amino groups on proteins.

In most mammalian cells, Acetyl-coenzyme A (Acetyl-CoA) is predominantly generated in the mitochondrial matrix by various metabolic circuitries, namely glycolysis, β-oxidation, and the catabolism of branched amino acids. Cytosolic Acetylcoenzyme A is the precursor of multiple anabolic reactions that underlie the synthesis of fatty acids and steroids, as well as specific amino acids including glutamate, proline, and arginine.

体内研究

Mice deprived of food (but with access to water ad libitum) for 24 hr exhibit a significant reduction in total Acetyl-coenzyme A (Acetyl-CoA) levels in several organs, including the heart and muscles, corresponding to a decrease in protein acetylation levels. However, the same experimental conditions have no major effects on Acetyl-coenzyme A concentrations in the brain and actually increase hepatic Acetyl-coenzyme A and protein acetylation levels. Ethanol intake augments Acetyl-coenzyme A levels in hepatic mitochondria

保存条件：

-20℃

UN码：

HazardClass：

危害声明：

安全说明：

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