中文名称: | 特立氟胺 促销 一键复制产品信息 | ||||
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英文名称: | Teriflunomide | ||||
别名: | 特立氟胺 A771726 HMR-1726 (Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide | ||||
CAS No: | 163451-81-8 | 分子式: | C12H9F3N2O2 | 分子量: | 270.21 |
CAS No: | 163451-81-8 | ||||
分子式: | C12H9F3N2O2 | ||||
分子量: | 270.21 | ||||
MDL: | MFCD00910058 |
一种来氟米特的活性代谢产物,它抑制嘧啶合成,因此有效降低T细胞和B细胞增殖。
Teriflunomide is the active metabolite of leflunomide. Teriflunomide is an immunomodulatory drug inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase. It is uncertain whether this explains its effect on MS lesions. Teriflunomide inhibits rapidly dividing cells, including activated T cells, which are thought to drive the disease process in MS. It has been found that teriflunomide blocks the transcription factor NF-κB.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )