| 中文名称: | (S)-(-)-Bay-K-8644 一键复制产品信息 | ||||
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| 英文名称: | (S)-(-)-Bay-K-8644 | ||||
| 别名: | (S)-(-)-Bay-K-8644 (S)-(-)-Bay-K-8644 | ||||
| CAS No: | 98625-26-4 | 分子式: | C16H15F3N2O4 | 分子量: | 356.3 |
| CAS No: | 98625-26-4 | ||||
| 分子式: | C16H15F3N2O4 | ||||
| 分子量: | 356.3 | ||||
基本信息
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产品编号： |
S10937 |
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产品名称： |
(S)-(-)-Bay-K-8644 |
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CAS: |
98625-26-4 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式： |
溶于液体 |
-80℃ |
6个月 |
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分子量： |
356.30 |
-20℃ |
1个月 |
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化学名： |
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Solubility (25°C)： |
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体外:
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DMSO |
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Ethanol |
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Water |
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体内(现配现用): |
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＜1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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制备储备液
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浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
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1mM |
2.8066mL |
14.0331mL |
28.0662mL |
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5mM |
0.5613mL |
2.8066mL |
5.6132mL |
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10mM |
0.2807mL |
1.4033mL |
2.8066mL |
生物活性
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产品描述 |
一种L型钙离子通道激动剂。 |
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靶点 |
EC50:32nM (IBa) |
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体外研究 |
(±)-Bay K 8644,a conventional racemic mixture of Bay K 8644,is widely used as an L-type Ca2+ channel agonist. Each optical isomer possesses opposite effects on IBa (R(+)-Bay K 8644 as an antagonist and (S)-(-)-Bay-K-8644 as an agonist.(S)-(-)-BayK-8644 can prevent the inhibitory actions of two distinct cyclic nucleotide pathways on IBa in gastric myocytes of the guinea pig antrum.The Ca2+ channel activity is enhanced by 3–30μM (S)-(-)-Bay-K-8644 an agonist of L-type Ca2+ channels.The interactions of two Ca2+ channel activators (S)-(-)-Bay-K-8644 and FPL 64176 is examined on smooth muscle L-type Ca2+ channels.FPL 64176 (300nM) causes a sustained contraction of rat tail artery strips.This contractile response is inhibited by approximately 70% by (S)-(-)-Bay-K-8644 (EC50=14nM).(S)-(-)-Bay-K-8644 (100nM) increases whole-cell Ca2+ currents in A7r5 smooth muscle cells but effectively blocks further stimulation by 1μM FPL 64176. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
