中文名称: | Pimonidazole 一键复制产品信息 | ||||
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英文名称: | Pimonidazole | ||||
别名: | 哌莫硝唑; 乏氧示踪剂 alpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol | ||||
CAS No: | 70132-50-2 | 分子式: | C11H18N4O3 | 分子量: | 254.29 |
CAS No: | 70132-50-2 | ||||
分子式: | C11H18N4O3 | ||||
分子量: | 254.29 |
一种缺氧标记物,用于瘤内缺氧和细胞增殖的补充性研究。Pimonidazole 通过与大分子的共价结合或通过被还原形成还原性代谢物后在缺氧细胞中积累,可用于定性和定量评估肿瘤缺氧。
Pimonidazole, also known as Ro 03-8799 and PD 126675, is a nitroimidazole drug with hypoxic selectivity and radiosensitizing property. Pimonidazole is reduced in hypoxic environments as in tumor cells, thereby it can be used as an hypoxia marker. In hypoxic cells, reduced pimonidazole binds to -SH-containing molecules such as glutathione and proteins, and the resulting complexes accumulated in tissues, thereby sensitizing cells to be more susceptible for radiation treatment.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )