| 中文名称: | 烯啶虫胺 一键复制产品信息 | ||||
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| 英文名称: | Nitenpyram | ||||
| 别名: | (E)-N-((6-氯吡啶-3-基)甲基)-N-乙基-N'-甲基-2-硝基乙烯-1,1-二胺 (E)-N-((6-Chloropyridin-3-yl)methyl)-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine | ||||
| CAS No: | 150824-47-8 | 分子式: | C11H15ClN4O2 | 分子量: | 270.72 |
| CAS No: | 150824-47-8 | ||||
| 分子式: | C11H15ClN4O2 | ||||
| 分子量: | 270.72 | ||||
基本信息
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产品编号： |
N11040 |
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产品名称： |
Nitenpyram |
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CAS: |
150824-47-8 |
储存条件 |
粉末 |
室温 |
四年 |
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分子式： |
溶于液体 |
-80℃(避光) |
6个月 |
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分子量： |
270.72 |
-20℃(避光) |
1个月 |
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化学名： |
(E)-N-((6-Chloropyridin-3-yl)methyl)-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine |
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Solubility (25°C)： |
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体外:
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DMSO |
54mg/mL (199.46mM) |
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Ethanol |
54mg/mL (199.46mM) |
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Water |
54mg/mL warmed with 50ºC water bath (199.46mM) |
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体内(现配现用): |
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＜1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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制备储备液
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浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
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1mM |
3.6939mL |
18.4693mL |
36.9385mL |
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5mM |
0.7388mL |
3.6939mL |
7.3877mL |
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10mM |
0.3694mL |
1.8469mL |
3.6939mL |
生物活性
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产品描述 |
一类新烟碱和昆虫烟碱型乙酰胆碱受体(nAChR)激动剂，IC50为14nM。Nitenpyram是一种口服速效杀虫剂，用于抑制猫狗等动物身上的吮吸昆虫。 |
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靶点 |
nAChR |
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体内研究 |
Nitenpyram is administered orally (1mg/kg) for the short-term control of fleas in dogs and cats.Fleas start to fall from the animals 30 minutes post-administration and one dose can protect animals for 1-2 days.Since Nitenpyram is highly lipophilic,it is administered orally after the meal in order to induce bile flow to help dissolve the chemical,thereby increasing GI absorption of the drug.It is rapidly and completely absorbed from the GI tract in less than 90 minutes and is completely excreted in urine within 48 hours after oral administration to dogs and cats.Nitenpyram undergoes hydroxylation,followed by conjugation in the liver.The conjugates of Nitenpyram are excreted in the urine and Nitenpyram is not accumulated in body tissues.The plasma half-life of Nitenpyram in dogs and cats are 3 and 8 hours,respectively.It is likely that animals with liver and/or kidney problems may have longer plasma half-life of Nitenpyram. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
