基本信息
|
产品编号： |
M10647 |
||||
|
产品名称： |
3-(Methylthio)propionic acid |
||||
|
CAS: |
646-01-5 |
储存条件 |
粉末 |
室温 |
四年 |
|
|
|
||||
|
分子式： |
溶于液体 |
-80℃ |
6个月 |
||
|
分子量： |
120.17 |
-20℃ |
1个月 |
||
|
化学名： |
3-Methylsulfanylpropionic acid |
||||
|
Solubility (25°C)： |
|||||
|
体外:
|
DMSO |
|
|||
|
Ethanol |
'mg/mL |
||||
|
Water |
|
||||
|
体内(现配现用): |
|
||||
|
＜1mg/ml表示微溶或不溶。 |
|||||
|
普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 |
|||||
|
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
|||||
制备储备液
|
浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
|
1mM |
8.3215mL |
41.6077mL |
83.2154mL |
|
5mM |
1.6643mL |
8.3215mL |
16.6431mL |
|
10mM |
0.8322mL |
4.1608mL |
8.3215mL |
生物活性
|
产品描述 |
是甲硫氨酸代谢的中间体。 |
|
靶点 |
Human Endogenous Metabolite |
|
体外研究 |
Methionine has consistently been shown to be the most toxic amino acid in experiments devised to assess the relative toxicity of dietary amino acids.3-methylthiopropionate is an intermediate in methionine catabolism in rat and monkey liver in vitro.This pathway appears to account for a major portion of methionine oxidation in vitro.Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts directly related to the concentration of methionine in the medium.The first intermediate in the pathway may be the keto acid,which is then oxidatively decarboxylated to 3-methylthiopropionic acid.The purified 3-MTPA has antifungal activity in assays using F.oxysporum as a model fungus.Daily measurements of shoot and root length shows severe inhibition of seed germination and root and shoot development at concentrations above 12mg for partially purified extracts.3-methylthiopropionic acid ethyl ester possesses potential anticarcinogenic properties by inducing differentiation in well-differentiated colon cancer cells.Treatment of RCM-1 cells for 4 days with 3-methylthiopropionic acid ethyl ester between the doses of 0.25 and 2mM progressively increases the percent area occupied by duct structures relative to the control,and also induces an increase in the number and the maximum diameter of the ducts in each culture plate. |
推荐实验方法(仅供参考)
|
细胞实验: |
|
|
RCM-1 cells are each plated into 35-mm plastic culture plates.Twenty-four hours after plating,cells are treated with 3-methylthiopropionic acid ethyl ester in 2mL of 10% FBS-RPMI+F12 for 4 days,and are counted by using a hemacytometer,after trypsinization with 0.25% trypsin and 1mM EDTA. |
|
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
