中文名称: | 诃子次酸 一键复制产品信息 | ||||
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英文名称: | Chebulic acid | ||||
别名: | 诃子次酸 Chebulic acid | ||||
CAS No: | 23725-05-5 | 分子式: | C14H12O11 | 分子量: | 356.24 |
CAS No: | 23725-05-5 | ||||
分子式: | C14H12O11 | ||||
分子量: | 356.24 |
一种从 Terminalia chebula 中分离出的酚羧酸化合物,具有很强的抗氧化活性,它打破了由晚期糖基化终产物 (AGEs) 诱导的蛋白质交联,抑制了 (AGEs) 的形成。Chebulic acid 对控制代谢参数升高、氧化应激和肾损害有效,支持其在糖尿病肾病中的有益作用。
Chebulic acid is a phenol that has been found in T. chebular and has diverse biological activities. It reduces production of reactive oxygen species in human umbilical vein endothelial cells induced by glyceraldehyde-related advanced glycation end products when used at a concentration of 100 µg/ml. Chebulic acid reduces glycer-AGE-induced adhesion of HUVECs to THP-1 monocytes. It induces Nrf2 nuclear translocation and glutathione synthesis and inhibits glycer-AGE-induced collagen accumulation, a marker of fibrosis, in LX-2 hepatic stellate cells. In vivo, chebulic acid increases serum insulin levels and reduces blood urea nitrogen levels, proteinuria, albuminuria, and serum glucose levels in a diabetic rat model of ischemia-reperfusion-induced nephropathy.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )