中文名称: | Camalexin 促销 一键复制产品信息 | ||||
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英文名称: | Camalexin | ||||
别名: | 2-(1H-indol-3-yl)thiazole;3-(2-Thiazolyl)-1H-indole;Camalexin;3-(Thiazol-2-yl)-1H-indole;Camalexine | ||||
CAS No: | 135531-86-1 | 分子式: | C11H8N2S | 分子量: | 200.26 |
CAS No: | 135531-86-1 | ||||
分子式: | C11H8N2S | ||||
分子量: | 200.26 |
基本信息
产品编号: |
C10727 |
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产品名称: |
Camalexin |
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CAS: |
135531-86-1 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式: |
溶于液体 |
-80℃ |
两年 |
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分子量 |
200.26 |
-20℃ |
一个月 |
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化学名: |
2-(1H-indol-3-yl)thiazole;3-(2-Thiazolyl)-1H-indole;Camalexin;3-(Thiazol-2-yl)-1H-indole;Camalexine |
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Solubility (25°C): |
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体外:
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DMSO |
125mg/mL(624.19mM;Need ultrasonic) |
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Ethanol |
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Water |
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体内(现配现用): |
1.请依序添加每种溶剂:10% DMSO→40% PEG300→5% Tween-80→45% saline Solubility:≥2.08mg/mL(10.39mM);Clear solution |
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此⽅案可获得≥2.08mg/mL(10.39mM,饱和度未知)的澄清溶液。以1mL⼯作液为例,取100μL20.8mg/mL的澄清DMSO储备液加到400μL PEG300中,混合均匀;向上述体系中加⼊50μL Tween-80,混合均匀;然后继续加⼊450μL⽣理盐⽔定容⾄1mL。 |
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2.请依序添加每种溶剂:10% DMSO→90% (20% SBE-β-CD in saline) Solubility:≥2.08mg/mL(10.39mM);Clear solution |
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此⽅案可获得≥2.08mg/mL(10.39mM,饱和度未知)的澄清溶液。以1mL⼯作液为例,取100μL20.8mg/mL的澄清DMSO储备液加到900μL20%的SBE-β-CD⽣理盐⽔⽔溶液中,混合均匀。 |
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3.请依序添加每种溶剂:10% DMSO→90% corn oil Solubility:≥2.08mg/mL(10.39mM);Clear solution |
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此⽅案可获得≥2.08mg/mL(10.39mM,饱和度未知)的澄清溶液,此⽅案不适⽤于实验周期在半个⽉以上的实验。以1mL⼯作液为例,取100μL20.8mg/mL的澄清DMSO储备液加到900μL⽟⽶油中,混合均匀。 |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
制备储备液
浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
1mM |
4.9935mL |
24.9675mL |
49.9351mL |
5mM |
0.9987mL |
4.9935mL |
9.9870mL |
10mM |
0.4994mL |
2.4968mL |
4.9935mL |
生物活性
产品描述 |
一种植物抗毒素,是从 Camelina sativa 和 Arabidopsis(十字花科植物)中分离出来的,具有抗菌,抗真菌,抗增殖和抗癌活性。 |
靶点 |
Reactive oxygen species (ROS) |
体外研究 |
Camalexin shows antiproliferative activity against a human breast cancer cell line. For the oomycetes Phytophthora and Pythium Nep1-like proteins (necrosis and ethylene-inducing peptide 1-like proteins) are the initial triggers of Camalexin synthesis and formation of reactive oxygen species (ROS). ROS appear to be of general relevance for Camalexin formation. Chemical induction of ROS, such as by application of acifluorfen, coincided with Camalexin synthesis. In a screen for enhanced susceptibility to Alternaria brassicicola the esa1 mutant is identified, which shows delayed Camalexin induction. Particularly in response to ROS inducing agents reduced Camalexin levels are synthesized. This crucial role for ESA1 is confirmed by the inability of esa1 mutants to synthesize Camalexin in response to Leptosphaeria maculans. An additional mutant that exhibits greatly reduced Camalexin accumulation is ups1, which is isolated on the basis of diminished expression of a tryptophan biosynthetic enzyme |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )