| 中文名称: | BMS-863233 | ||||
|---|---|---|---|---|---|
| 英文名称: | BMS-863233 | ||||
| 别名: | 8-氯-2-(2S)-2-吡咯烷基苯并呋喃并[3,2-d]嘧啶-4(3H)-酮 XL413; (S)-8-chloro-2-(pyrrolidin-2-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one | ||||
| CAS No: | 1169558-38-6 | 分子式: | C14H12ClN3O2 | 分子量: | 289.72 |
| CAS No: | 1169558-38-6 | ||||
| 分子式: | C14H12ClN3O2 | ||||
| 分子量: | 289.72 | ||||
一种有效的选择性的ATP竞争性的Cdc7抑制剂。
BMS-863233 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. CDC7 kinase inhibitor BMS-863233 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells. CDC7, a serine-threonine kinase overexpressed in a variety of tumor cell types, plays an essential role in the initiation of DNA replication by activating origins of replication.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
