| 中文名称: | Ximelagatran | ||||
|---|---|---|---|---|---|
| 英文名称: | Ximelagatran | ||||
| 别名: | ((R)-1-环己基-2-((S)-2-((4-(N-羟基氨基甲酰胺基)苄基)氨基甲酰)壬苷-1-基)-2-氧乙基)甘氨酸乙酯 H 376/95；Ethyl ((R)-1-cyclohexyl-2-((S)-2-((4-(N-hydroxycarbamimidoyl)benzyl)carbamoyl)azetidin-1-yl)-2-oxoethyl)glycinate | ||||
| CAS No: | 192939-46-1 | 分子式: | C24H35N5O5 | 分子量: | 473.57 |
| CAS No: | 192939-46-1 | ||||
| 分子式: | C24H35N5O5 | ||||
| 分子量: | 473.57 | ||||
一种口服活性凝血酶抑制剂，可选择性和竞争性地抑制游离和凝块结合的凝血酶。Ximelagatran 还是一种抗凝药物，具有快速起效的抗凝作用，可预测的，剂量依赖性的药代动力学和药效学。
Ximelagatran (Exanta or Exarta, H 376/95) is an anticoagulant that has been investigated extensively as a replacement for warfarin[1] that would overcome the problematic dietary, drug interaction, and monitoring issues associated with warfarin therapy. In 2006, this drug was discontinued due to hepatotoxicity (liver damage). Ximelagatran, a direct thrombin inhibitor,[3] was the first member of this class that can be taken orally. It acts solely by inhibiting the actions of thrombin. It is taken orally twice daily, and rapidly absorbed by the small intestine. Ximelagatran is a prodrug, being converted in vivo to the active agent melagatran.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
