中文名称: | Ilomastat | ||||
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英文名称: | Ilomastat | ||||
别名: | 伊洛马司他;(R)-N1-((S)-3-(1H-吲哚-3-基)-1-(甲胺基)-1-氧代丙-2-基)-N4-羟基-2-异丁基琥珀酰胺 GM6001; Galardin | ||||
CAS No: | 142880-36-2 | 分子式: | C20H28N4O4 | 分子量: | 388.46 |
CAS No: | 142880-36-2 | ||||
分子式: | C20H28N4O4 | ||||
分子量: | 388.46 |
一种有效、广谱的基质金属蛋白酶 (MMP) 抑制剂,能够抑制 MMP 的活性。
Ilomastat, also known as GM6001 and galardin, is a broad-spectrum matrix metalloproteinase inhibitor with potential anticancer activity. GM6001 is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc. Examples of enzymes that ilomastat inhibit include thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )