中文名称: | Bradykinin (2-9) (Synonyms: Des-Arg1-bradykinin) | ||||
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英文名称: | Bradykinin (2-9) | ||||
别名: | 舒缓激肽片段2-9;去-精氨酰-血管舒缓激肽 Des-Arg1-bradykinin;Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg | ||||
CAS No: | 16875-11-9 | 分子式: | C44H61N11O10 | 分子量: | 904.02 |
CAS No: | 16875-11-9 | ||||
分子式: | C44H61N11O10 | ||||
分子量: | 904.02 |
基本信息
产品编号:B10857 |
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产品名称:Bradykinin (2-9) |
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CAS: |
16875-11-9 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式: |
溶于液体 |
-80℃ |
六个月 |
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分子量: |
904.02 |
-20℃ |
一个月 |
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化学名: |
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Solubility (25°C) |
体外 |
DMSO |
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Ethanol |
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Water |
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体内(现配现用) |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
制备储备液
浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
1mM |
1.1062mL |
5.5309mL |
11.0617mL |
5mM |
0.2212mL |
1.1062mL |
2.2123mL |
10mM |
0.1106mL |
0.5531mL |
1.1062mL |
生物活性
产品描述 |
一种氨基截短的激肽肽。Bradykinin (2-9) 是由氨基肽酶 P 切割形成的一种 Bradykinin 代谢物。 |
靶点/IC50 |
Bradykinin Receptor |
体外研究 |
The Bradykinin peptide system is a tissue-based system with potent cardiovascular and renal effects. To investigate the regulation of this system, a highly sensitive amino terminal-directed radioimmunoassay that, with high performance liquid chromatography, enables the measurement of Bradykinin-(1-7), Bradykinin-(1-8),and Bradykinin-(1-9), is developed.Together with a carboxy terminal-directed radioimmunoassay, Bradykinin peptides in rat kidney and blood are characterized.The predominant Bradykinin peptides in kidney are Bradykinin-(1-9) (~100 fmol/g wet weight of tissue) and Bradykinin-(1-7) (~70 fmol/g), with low levels of Bradykinin-(1-8) (~8 fmol/g) and Bradykinin-(4-9) (~12 fmol/g) detectable;Bradykinin-(2-9) and Bradykinin-(3-9) are below the limits of detection. In blood, the levels of Bradykinin-(1-9) are very low (~2 fmol/ml),and other Bradykinin peptides are below the limits ofdetection. Administration of the angiotensin converting enzyme (ACE) inhibitor Perindopril is associated with an approximate twofold increase in renal levels of Bradykinin-(1-8) and Bradykinin-(1-9) and a decrease in the Bradykinin-(1-7)/Bradykinin-(1-9) ratio. The amino terminal-directed radioimmunoassay is also applied to heart, aorta, brown adipose tissue, adrenal, lung, and brain. For these tissues,Bradykinin-(1-7) and Bradykinin-(1-9) are of similar abundance (16-340 fmol/g), with lower levels of Bradykinin-(1-8). |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )