中文名称: | UK-5099 促销 | ||||
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英文名称: | UK-5099 | ||||
别名: | 2-氰基-3-(1-苯基-1H-吲哚-3-基)丙烯酸 PF-1005023;2-Cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid | ||||
CAS No: | 56396-35-1 | 分子式: | C18H12N2O2 | 分子量: | 288.3 |
CAS No: | 56396-35-1 | ||||
分子式: | C18H12N2O2 | ||||
分子量: | 288.3 |
一种线粒体丙酮酸转运蛋白(MPC)的有效抑制剂,抑制丙酮酸依赖性O2消耗的IC50值为50nM。
UK-5099 is a specific and potent mitochondrial pyruvate carrier blocker (MCK blocker). The UK5099 treated cells showed significantly higher proportion of side population (SP) fraction and expressed higher levels of stemness markers Oct3/4 and Nanog. Chemosensitivity examinations revealed that the UK5099 treated cells became more resistant to chemotherapy compared to the non-treated cells. MPC blocker (UK5099) application may be an ideal model for Warburg effect studies
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )