中文名称: | 托吡酯 | ||||
---|---|---|---|---|---|
英文名称: | Topiramate | ||||
别名: | ((3aS,5aR,8aR,8bS)-2,2,7,7-四甲基四氢-3aH-双([1,3]二氧杂环己烷基)〔4,5-b:4' ,5'-d]吡喃-3a-基)甲基氨基磺酸酯 McN4853;RWJ17021 | ||||
CAS No: | 97240-79-4 | 分子式: | C12H21NO8S | 分子量: | 339.36 |
CAS No: | 97240-79-4 | ||||
分子式: | C12H21NO8S | ||||
分子量: | 339.36 |
一种广谱抗癫痫药。Topiramate也是一种GluR5受体拮抗剂,可通过增强GABAergic活性,抑制kainate/AMPA受体,抑制钠和钙通道的电压敏感,增加钾电导并抑制carbonicanhydrase来产生抗癫痫作用。
Topiramate (brand name Topamax) is an anticonvulsant (antiepilepsy) drug. In late 2012, topiramate was approved by the United States Food and Drug Administration (FDA) in combination with phentermine for weight loss. The drug had previously been used off-label for this purpose. Topiramate is used to treat epilepsy in children and adults, and it was originally used as an anticonvulsant. In children, it is indicated for the treatment of Lennox-Gastaut syndrome, a disorder that causes seizures and developmental delay.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )