中文名称: | TH-263 | ||||
---|---|---|---|---|---|
英文名称: | TH-263 | ||||
别名: | N-Benzyl-4-(N-benzylsulfamoyl)benzamide | ||||
CAS No: | 313520-94-4 | 分子式: | C21H20N2O3S | 分子量: | 380.46 |
CAS No: | 313520-94-4 | ||||
分子式: | C21H20N2O3S | ||||
分子量: | 380.46 |
一种二芳基磺酰胺衍生物,对 LIMK1 和 LIMK2 均无抑制活性,可以作为 TH-257 的阴性对照。
TH-263 is an inactive analog control for the type III allosteric LIM-kinase (LIMK) inhibitors TH-257, TH-255 and TH-251. LIM kinases belong to the family of cytoplasmic tyrosine-like kinases with dual specificity (serine/threonine and tyrosine). However, known LIMK substrate are usually phosphorylated at serine and threonine residues LIM kinases comprises LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2) which show 50% sequence identity in human. Both LIMK1 and LIMK2 present with a unique domain organization containing two N-terminal LIM domains, a PDZ domain, a proline/serine-rich domain and a C-terminal kinase domain.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )