| 中文名称: | 盐酸替莫普利 | ||||
|---|---|---|---|---|---|
| 英文名称: | Temocapril hydrochloride | ||||
| 别名: | 盐酸替莫普利 2-[(2S,6R)-6-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid;hydrochloride | ||||
| CAS No: | 110221-44-8 | 分子式: | C23H28N2O5S2.HCl | 分子量: | 513.07 |
| CAS No: | 110221-44-8 | ||||
| 分子式: | C23H28N2O5S2.HCl | ||||
| 分子量: | 513.07 | ||||
一种血管紧张素转化酶 (ACE) 抑制剂。Temocapril hydrochloride 可以用于高血压、充血性心力衰竭、急性心肌梗死、胰岛素抵抗和肾脏疾病的研究。
Temocapril is a prodrug of the ACE inhibitor, temocaprilat (IC50 = 3.6 and 7.6 nM in isolated rat lung and aorta, respectively).1 Upon oral administration it is rapidly deesterified to the active form, which remains long acting until excreted in bile and urine.1 In clinical trials, it has been used to reduce blood pressure, improve endothelial dysfunction, and prevent vascular remodeling, as well as improve insulin sensitivity and renal function in certain hypertensive or diabetic conditions.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
