中文名称: | 拓扑替康盐酸盐 促销 | ||||
---|---|---|---|---|---|
英文名称: | Topotecan HCl | ||||
别名: | 盐酸拓扑替康 Topotecan hydrochloride | ||||
CAS No: | 119413-54-6 | 分子式: | C23H24ClN3O5 | 分子量: | 457.9 |
CAS No: | 119413-54-6 | ||||
分子式: | C23H24ClN3O5 | ||||
分子量: | 457.9 | ||||
MDL: | MFCD00866235 | EINEC: | 609699 | ||
EINEC: | 609699 |
一种拓扑异构酶I抑制剂。
Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )