中文名称: | 链球菌溶血素O | ||||
---|---|---|---|---|---|
英文名称: | Streptolysin O | ||||
别名: | 链球菌溶血素 O Streptolysin O | ||||
CAS No: | 98072-47-0 | ||||
CAS No: | 98072-47-0 |
包装规格:
10ku in glass bottle
产品简介:
Streptolysin O,A组链球菌毒素,是一个氧不稳定原型胆固醇结合细菌外毒素。Streptolysin O 导致细胞裂解和心脏毒性。Streptolysin O 用于细胞膜的可控渗透性。Streptolysin O 以两种形式存在,即还原活性状态和氧化可逆不活动状态。
体外研究:
Streptolysin O is a labile toxin, and, with time, activity is irreversibly lost. The rate of activity loss is slowed by incubation with 0.1 M 2-mercaptoethanol or 0.01 M ethylenediaminetetraacetic acid (EDTA).
Streptolysin O, belongs to the group of thiol-activated toxins, is a secreted virulence factor of GAS that induces apoptosis in neutrophils and macrophages at later time points (~4 h). Streptolysin O induces eukaryotic cell lysis in a cholesterol-dependent manner, is highly upregulated in the GAS M1T1 clone during bloodstream dissemination. Streptolysin O is known to promote Group A Streptococcus (GAS) resistance to phagocytic clearance by neutrophils, a critical first element of host defense against invasive bacterial infection.
注意事项:
1、为了您的安全和健康,请穿实验服并戴一次性手套操作。
2、以上信息仅做参考交流之用。
2、以上信息仅做参考交流之用。
保存条件:
2-8℃
UN码:
HazardClass:
危害声明:
安全说明:
搜索质检报告(COA)
参考文献 & 客户发表文献
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )