| 中文名称: | Small Cardioactive Peptide B SCPB | ||||
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| 英文名称: | Small Cardioactive Peptide B SCPB | ||||
| CAS No: | 84746-43-0 | 分子式: | C52H80N14O11S2 | 分子量: | 1141.41 |
| CAS No: | 84746-43-0 | ||||
| 分子式: | C52H80N14O11S2 | ||||
| 分子量: | 1141.41 | ||||
基本信息
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产品编号： |
S10834 |
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产品名称： |
Small Cardioactive Peptide B SCPB |
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CAS: |
84746-43-0 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式： |
溶于液体 |
-80℃(避光，储存于氮) |
6个月 |
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分子量： |
1141.41 |
-20℃(避光，储存于氮) |
1个月 |
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化学名： |
MET-ASN--LEU-ALA-PHE-PRO-ARG-MET (MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET AMIDE) |
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Solubility (25°C)： |
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体外:
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DMSO |
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Ethanol |
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Water |
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体内(现配现用): |
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＜1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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制备储备液
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浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
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1mM |
0.8761mL |
4.3805mL |
8.7611mL |
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5mM |
0.1752mL |
0.8761mL |
1.7522mL |
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10mM |
0.0876mL |
0.4381mL |
0.8761mL |
生物活性
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产品描述 |
一种神经活性肽，刺激心脏和鳃组织的颗粒组分中的腺苷酸环化酶 (adenylate cyclase) 活性，EC50 分别为 0.1 和 1.0μM。 |
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靶点 |
0.1μM (adenylate cyclase, in heart tissues),1.0μM (adenylate cyclase, in gill tissues) |
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体外研究 |
Small cardioactive peptide B (SCPB) is a neurally active peptide endogenous to Aplysia.Small cardioactive peptide B (SCPB) possesses cardioexcitatory effects in Aplysia and reported a threshold concentration of 0.01nM for both native and synthetic Small cardioactive peptide B (SCPB) stimulated effects on the isolated heart. Effects of Small Cardioactive Peptide B (SCPB) on the physiology of the isolated heart and gill preparations from the mollusc Aplysia californica were examined.In addition,the effects of Small Cardioactive Peptide B (SCPB) and FMRFamide (Phe-Met-Arg-Phe-NH2) on adenylate cyclase activity are compared in particulate fractions of heart and gill tissues,respectively.Small Cardioactive Peptide B (SCPB) is found to exert dose-dependent,reversible changes in cardiac activity when perfused through the isolated heart.The EC50 values effecting changes in heart rate and force of contraction are 0.03 and 0.3nM,respectively; minimum concentrations find to effect changes in heart rate and force of contraction are normally 0.001 and 1pM,respectively. When perfused through the isolated gill,Small Cardioactive Peptide B (SCPB) is found to suppress the gill withdrawal response amplitude with a threshold concentration of 0.01pM and an EC50 value of 0.03nM.Suppression of the gill withdrawal response amplitude by Small Cardioactive Peptide B (SCPB)is found to be dose dependent and reversible up to a concentration of 1nM. At higher concentrations, the suppression tended to persist irreversibly.Small Cardioactive Peptide B (SCPB) stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with an EC50 of 0.1 and 1.0μM,respectively. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
