中文名称: | SPDB | ||||
---|---|---|---|---|---|
英文名称: | SPDB | ||||
别名: | N-Succinimidyl 4-(2-pyridyldithio)butanoate;SPDB;SPDB crosslinker;2,5-dioxopyrrolidin-1-yl 4-(pyridin-2-yldisulfanyl)butanoate | ||||
CAS No: | 115088-06-7 | 分子式: | C13H14N2O4S2 | 分子量: | 326.39 |
CAS No: | 115088-06-7 | ||||
分子式: | C13H14N2O4S2 | ||||
分子量: | 326.39 |
包装规格:
5mg 10mg 50mg in glass bottle
溶解性:
溶于乙醇(100 mg/mL超声)
产品描述:
一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)
SPDB is useful heterobifunctional cross-linker, which is widely used to conjugate a small molecule drug to a targeted carrier (such as antibody, enzyme, protein and polymer). SPDB can be used to make ADC (antobody drug conjugate. Conjugated to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used.
SPDB is useful heterobifunctional cross-linker, which is widely used to conjugate a small molecule drug to a targeted carrier (such as antibody, enzyme, protein and polymer). SPDB can be used to make ADC (antobody drug conjugate. Conjugated to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used.
保存条件:
-20℃
UN码:
HazardClass:
危害声明:
安全说明:
搜索质检报告(COA)
参考文献 & 客户发表文献
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )