中文名称: | 乙胺嘧啶 | ||||
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英文名称: | Pyrimethamine | ||||
别名: | 乙胺嘧啶 Pirimecidan; Pirimetamin; RP 4753 | ||||
CAS No: | 58-14-0 | 分子式: | C12H13ClN4 | 分子量: | 248.71 |
CAS No: | 58-14-0 | ||||
分子式: | C12H13ClN4 | ||||
分子量: | 248.71 | ||||
MDL: | MFCD00057350 |
可通过抑制二氢叶酸还原酶(DHFR)干扰四氢叶酸的合成,可作用于原生动物的感染。
Pyrimethamine is an antiprotozoal agent that inhibits the protozoal enzyme dihydrofolate reductase. Pyrimethamine prevents the production of tetrahydrofolic acid, an essential coenzyme involved in DNA and RNA synthesis. Pyrimethamine is a dihydrofolate reductase inhibitor antimalarial. The mechanism of action of pyrimethamine is as a Dihydrofolate Reductase Inhibitor. Pyrimethamine has also been found to limit the expression of the superoxide dismutase 1 gene, a protein involved in amyotrophic lateral sclerosis.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )