中文名称: | 原花青素 | ||||
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英文名称: | Proanthocyanidins | ||||
别名: | 原花青素 OPC | ||||
CAS No: | 20347-71-1 | 分子式: | C30H26O13 | 分子量: | 594.52 |
CAS No: | 20347-71-1 | ||||
分子式: | C30H26O13 | ||||
分子量: | 594.52 |
基本信息
产品编号:P10585 |
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产品名称:Proanthocyanidins |
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CAS: |
20347-71-1 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式: |
溶于液体 |
-80℃ |
两年 |
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分子量 |
594.52 |
-20℃ |
一个月 |
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化学名: |
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Solubility (25°C) |
体外 |
DMSO |
100mg/mL (168.2mM) |
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Ethanol |
100mg/mL (168.2mM) |
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Water |
Insoluble |
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体内 |
现配现用 |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
制备储备液
浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
1mM |
1.6820mL |
8.4101mL |
16.8203mL |
5mM |
0.3364mL |
1.6820mL |
3.3641mL |
10mM |
0.1682mL |
0.8410mL |
1.6820mL |
50mM |
0.0336mL |
0.1682mL |
0.3364mL |
生物活性
产品描述 |
一类在高等植物中广泛分布的多酚化合物,由亲电子黄烷酰基单元组成,可用作抗氧化剂和抗癌剂。 |
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靶点/IC50 |
Bacterial |
Fungal |
体外研究 |
Proanthocyanidins are present in plants as complex mixtures of polymers. Predominant food sources are red wine, tea,chocolate and fruits like grapes, apples, pears, and cranberries.The most interesting antibacterial activity of Proanthocyanidins is related to their presence in cranberries (Vaccinium macrocarpon Ait.). A number of clinical trials have demonstrated the effectiveness of cranberry consumption in preventing urinary tract infections (UTIs). Although UTIs can be caused by many microorganisms, more than 85% are caused by Escherichia coli. The presence of P-fimbriae on E. coli, which are proteinaceous fibers on the bacterial cell wall, has been clearly established as a virulence factor, since they are responsible by producing adhesions for adherence to uroepithelial cells. Recently, it is demonstrated that cranberry Proanthocyanidins might inhibit P-fimbriated E. coli from adhering to uroepithelial cells. The antiadhesion activity of cranberry juice appears to be related to the presence of Proanthocyanidins with at least one A-type linkage. |
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体内研究 |
The effects of cacao liquor Proanthocyanidins on 2- amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced mutagenesis in vivo carcinogenesis in female Sprague-Dawley rats are investigated. In the Ames assay, Proanthocyanidins shows strong antimutagenic effects when assayed in the presence of S-9 mixture. They also inhibit significantly rat pancreatic carcinogenesis in the initiation stage, but not mammary carcinogenesis. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )