中文名称: | Mephenytoin | ||||
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英文名称: | Mephenytoin | ||||
别名: | 美芬妥因;5-乙基-3-甲基-5-苯基咪唑烷-2,4-二酮 5-Ethyl-3-methyl-5-phenylimidazolidine-2,4-dione | ||||
CAS No: | 50-12-4 | 分子式: | C12H14N2O2 | 分子量: | 218.25 |
CAS No: | 50-12-4 | ||||
分子式: | C12H14N2O2 | ||||
分子量: | 218.25 |
一种抗惊厥剂,是CYP2C19和CYP2B6的底物。
Mephenytoin (racemic) is a hydantoin, used as an anticonvulsant. It was introduced approximately 10 years after phenytoin, in the late 1940s. The significant metabolite of mephenytoin is nirvanol (5-ethyl-5-phenylhydantoin), which was the first hydantoin (briefly used as a hypnotic). However, nirvanol is quite toxic and mephenytoin was only considered after other less toxic anticonvulsants had failed. It can cause potentially fatal blood dyscrasia in 1% of patients. Mephenytoin is no longer available in the US or the UK. It is still studied largely because of its interesting hydroxylation polymorphism.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )