中文名称: | 美喹他嗪 | ||||
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英文名称: | Mequitazine | ||||
别名: | 美喹他嗪;甲喹吩嗪;甲噻吩嗪;玻丽玛朗 LM-209 | ||||
CAS No: | 29216-28-2 | 分子式: | C20H22N2S | 分子量: | 322.47 |
CAS No: | 29216-28-2 | ||||
分子式: | C20H22N2S | ||||
分子量: | 322.47 | ||||
EINEC: | 249-521-7 | ||||
EINEC: | 249-521-7 |
基本信息
产品编号: |
M11216 |
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产品名称: |
Mequitazine |
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CAS: |
29216-28-2 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式: |
溶于液体 |
-80℃ |
6个月 |
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分子量: |
322.47 |
-20℃ |
1个月 |
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化学名: |
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Solubility (25°C): |
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体外:
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DMSO |
32mg/mL (99.23mM) |
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Ethanol |
31mg/mL (96.13mM) |
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Water |
Insoluble |
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体内(现配现用): |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
制备储备液
浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
1mM |
3.1011mL |
15.5053mL |
31.0106mL |
5mM |
0.6202mL |
3.1011mL |
6.2021mL |
10mM |
0.3101mL |
1.5505mL |
3.1011mL |
50mM |
0.0620mL |
0.3101mL |
0.6202mL |
生物活性
产品描述 |
一种有效的,非依赖性和长效的组胺H1拮抗剂。 |
靶点 |
Histamine Receptor |
体外研究 |
Mequitazine is a potent H1-receptors selective antihistaminic drug widely studied and used for allergic disorders such as hay fever and urticaria.Mequitazine demonstrates significant bactericidal effects against all the tested clinical isolates including Ps.aeruginosa.Its effect against the Gram-positive isolates is more pronounced. |
体内研究 |
Mequitazine and clemizole antagonize the effect of histamine in guinea-pig ileum competitively.Mequitazine at 107 produces a parallel shift of the dose-response curve to acetylcholine in the rat duodenum.Mequitazine at highest concentration shows anticholinergic activity.Mequitazine inhibits contractile responses to KCl,phenylephrine (PE),5-hydroxytryptamine (5-HT),and Ca2+in rat aorta. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )