| 中文名称: | 串珠镰刀菌素钠盐 | ||||
|---|---|---|---|---|---|
| 英文名称: | Moniliformin sodium salt | ||||
| 别名: | 1-羟基-1-环丁烯-3,4-二酮钠;串珠镰刀菌素;串珠镰刀菌素钾盐;3-羟基-3-环丁烯二酮钠盐 Moniliformin sodium salt solution, 100 mug/mL in acetonitrile: water, analytical standard | ||||
| CAS No: | 71376-34-6 | 分子式: | C4HNaO3 | 分子量: | 120.04 |
| CAS No: | 71376-34-6 | ||||
| 分子式: | C4HNaO3 | ||||
| 分子量: | 120.04 | ||||
包装规格：
1mg in glass bottle
产品简介：
Moniliformin sodium salt是提取自镰孢镰刀菌中的有效的霉菌毒素
溶解性：
溶于DMSO（≥ 45 mg/mL)
储备液保存：
-80°C, 6 months; -20°C, 1 month
体内实验：
1、请依序添加每种溶剂： PBS
Solubility: 33.33 mg/mL (277.66 mM); Clear solution; Need ultrasonic
＜1mg/ml表示微溶或不溶。
普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
Solubility: 33.33 mg/mL (277.66 mM); Clear solution; Need ultrasonic
＜1mg/ml表示微溶或不溶。
普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
体外研究：
Fusarium moniliforme NRRL 6322 produces about 600 mg of recoverable moniliformin, a mycotoxic metabolite, per kg of corn grit medium. Several strains of Fusarium moniliforme produce in laboratory culture more than 800 mg of moniliformin per kg of growth substrate[1]. Monocytes-derived macrophages exposed to moniliformin during the differentiation process present a decrease of endocytosis ability, and a decrease of CD71 and HLA-DR expression.
体内研究：
Moniliformin is less toxic to mice, with an LD50 of 20.9 mg per kg for the females and 29.1 mg per kg of body weight for the males. As in the case of the chicks, mice surviving the toxin demonstrated no ill effects; the mice or chicks that died became recumbent in 4 to 6 h after treatment and died within 24 h. In 4-day-old chicken embryos, a sharp LD50 of 2.8 μg per embryo is obtained with no overt gross teratogenic effects in the survivors. Rats treated with the highest dose of moniliformin show decreased activity followed by acute heart failure and death. The rats of the lower doses (<9mg/kg b.w.) show no signs of toxicity. The daily intake of moniliformin strongly reduces the phagocytic activity of neutrophils in all dose groups. The decrease continued in the satellite group during the follow-up period, indicating a severe impact on the immune system and a LOAEL value of 3mg/kg b.w. for moniliformin. Moniliformin is rapidly excreted into urine, ranging between 20.2 and 31.5% daily and shows no signs of accumulation. The concentration of moniliformin in faeces is less than 2%, which suggests efficient absorption from the gastrointestinal tract.
保存条件：
-20℃
UN码：
HazardClass：
危害声明：
安全说明：
搜索质检报告(COA)
参考文献 & 客户发表文献
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
