中文名称: | 氟哌啶醇盐酸盐 | ||||
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英文名称: | Haloperidol hydrochloride | ||||
别名: | 氟哌啶醇盐酸盐 Haloperidol hydrochloride | ||||
CAS No: | 1511-16-6 | 分子式: | C21H24Cl2FNO2 | 分子量: | 412.33 |
CAS No: | 1511-16-6 | ||||
分子式: | C21H24Cl2FNO2 | ||||
分子量: | 412.33 |
基本信息
产品编号: |
H10404 |
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产品名称: |
Haloperidol hydrochloride |
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CAS: |
1511-16-6 |
储存条件 |
粉末 |
-20℃ |
四年 |
分子式: |
溶于液体 |
-80℃ |
二年 |
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分子量: |
412.33 |
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化学名: |
1-Butanone,4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-,hydrochloride (1:1) |
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Solubility (25°C): |
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体外:
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DMSO |
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Ethanol |
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Water |
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体内(现配现用): |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
生物活性
产品描述 |
一种有效的 dopamine D2 receptor 拮抗剂。 |
靶点 |
Dopamine Receptor |
体内研究 |
Haloperidol (1mg) intra-arterially attenuates the dopamine-induced pancreatic secretion.Haloperidol (3mg) completely inhibits the action of 10μg of dopamine in the pancreas of the dogs.Haloperidol (10mg/kg) as well as chlorpromazine (CPZ,15mg/kg) blocks mescaline-induced altered behavior within 7 to 10 minutes when injected into the mice 45 minutes after 50mg/kg (2µc) of mescaline. Haloperidol has no effect on mescaline disappearance. |
推荐实验方法(仅供参考)
动物实验: |
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Male albino mice of Swiss-Webster strain (33-36g) are used,and all substances are given by i.p.injection in a volume of 0.5mL.CPZ,haloperidoi and mescaline are all in time form of timeir imydrochlorides and the dose solutions are prepared at concentrations of 1.0,0.66 and 3.3mg/mL of 0.9% saline,respectively.The doses are:CPZ,15mg/kg;haloperidol,10mg/kg;mescaline,50mg/kg.Mice are pretreated with either CPZ or haloperidol 30 minutes before administration of mescaline.In some instances CPZ is injected 45 minutes after mescaline.Time animals are hmoused individually in a plexiglas cage and the gross behavior and locomotor activity.At selected intervals after mescaline,groups of mice are sacrificed by decapitation.Plasma is separated and stored at -20℃. The brain,liver,kidney,lung,spleen and heart are frozen on dry ice and stored at -20℃ for 18 to 20 hours before they are used for assays. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )