| 中文名称: | Glimepiride | ||||
|---|---|---|---|---|---|
| 英文名称: | Glimepiride | ||||
| 别名: | 3-乙基-4-甲基-N-(4-(N-((反式-4-甲基环己基)氨甲酰)磺胺基)苯乙基)-2-氧代-2,5-二氢-1H-吡咯-1-甲酰胺；格列美脲 Glimperide; HOE-490；4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide | ||||
| CAS No: | 93479-97-1 | 分子式: | C24H34N4O5S | 分子量: | 490.62 |
| CAS No: | 93479-97-1 | ||||
| 分子式: | C24H34N4O5S | ||||
| 分子量: | 490.62 | ||||
| EINEC: | 7083 | ||||
| EINEC: | 7083 | ||||
一种中长效的磺酰脲类抗糖尿病化合物，ED50为 182 μg/k。
Glimepiride is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, glimepiride increases the activity of intracellular insulin receptors. Glimepiride increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases protein expression of glucose transports 1 and 4, and is a potent KIR channel blocker.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
