中文名称: | 盐酸依氟乌氨酸 | ||||
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英文名称: | Eflornithine hydrochloride | ||||
别名: | 盐酸依氟乌氨酸;盐酸依氟鸟氨酸;盐酸恩氟沙星;盐酸依氟鸟氨酸无水物;2-(二氟甲基)-DL-鸟氨酸;依氟鸟氨酸 DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride | ||||
CAS No: | 68278-23-9 | 分子式: | C6H12F2N2O2.HCl | 分子量: | 218.63 |
CAS No: | 68278-23-9 | ||||
分子式: | C6H12F2N2O2.HCl | ||||
分子量: | 218.63 | ||||
EINEC: | 269-532-0 | ||||
EINEC: | 269-532-0 |
包装规格:
10mg in glass bottle
产品描述:
一种酶鸟氨酸脱羧酶的特异性不可逆抑制剂。Eflornithine 可用于研究非洲锥虫病和女性面部毛发过度生长。
Eflornithine, also known as Difluoromethylornithine, is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells.
Eflornithine, also known as Difluoromethylornithine, is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells.
保存条件:
-20℃
UN码:
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质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
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用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )