| 中文名称: | Emapunil | ||||
|---|---|---|---|---|---|
| 英文名称: | Emapunil | ||||
| 别名: | Emapunil AC-5216; XBD-173 | ||||
| CAS No: | 226954-04-7 | 分子式: | C23H23N5O2 | 分子量: | 401.47 |
| CAS No: | 226954-04-7 | ||||
| 分子式: | C23H23N5O2 | ||||
| 分子量: | 401.47 | ||||
一种口服有效的、选择性的 TSPO (一种线粒体苯二氮受体) 的配体，在多种动物模型中表现出抗焦虑和抗抑郁活性。
Emapunil, also known as AC-5216 and XBD-173, is a novel mitochondrial benzodiazepine receptor ligand (MBR ligand). AC-5216 showed high affinity for MBRs prepared from rat whole brain (Ki 0.297 nm), rat glioma cells (IC50 3.04 nm) and human glioma cells (IC50 2.73 nm), but only negligible affinity for the other main receptors including central benzodiazepine receptors. AC-5216 produced anti-anxiety effects in the Vogel-type conflict test in rats, and in the light/dark box and social interaction tests in mice at 0.1-3, 0.003-0.01 and 0.01-0.3 mg kg(-1), p.o., respectively.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
