| 中文名称: | 马来酸依那普利 | ||||
|---|---|---|---|---|---|
| 英文名称: | Enalapril maleate | ||||
| 别名: | (S)-1-((S)-2-(((S)-1-乙氧基-1-氧代-4-苯基丁-2-基)氨基)丙酰基)吡咯烷-2-羧酸马来酸盐 MK-421 maleate;(S)-1-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carboxylic acid Maleate | ||||
| CAS No: | 76095-16-4 | 分子式: | C24H32N2O9 | 分子量: | 492.52 |
| CAS No: | 76095-16-4 | ||||
| 分子式: | C24H32N2O9 | ||||
| 分子量: | 492.52 | ||||
| EINEC: | 278-375-7 | ||||
| EINEC: | 278-375-7 | ||||
Enalapril 的活性代谢物，是血管紧张素转化酶（ACE）抑制剂。
Enalapril maleate is an effective and potent angiotensin-converting enzyme inhibitor that is used to treat hypertension and heart failure. The compound has been used to study diabetic angiopathy in diabetic rats and inhibition of ACE in hog plasma. ACE inhibitors disturb the enin-angiotensin- aldosterone system. As a prodrug, enalapril is converted by de-esterification into its active form enalaprilat. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Enalapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
