中文名称: | Esomeprazole potassium salt | ||||
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英文名称: | Esomeprazole potassium salt | ||||
别名: | Esomeprazole potassium salt (S)-Omeprazole potassium salt | ||||
CAS No: | 1198768-91-0 | 分子式: | C17H19MgN3O3S | 分子量: | 369.72 |
CAS No: | 1198768-91-0 | ||||
分子式: | C17H19MgN3O3S | ||||
分子量: | 369.72 |
基本信息
产品编号: |
E10483 |
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产品名称: |
Esomeprazole potassium salt |
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CAS: |
1198768-91-0 |
储存条件 |
粉末 |
-20℃ |
四年 |
分子式: |
溶于液体 |
-80℃ |
二年 |
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分子量: |
369.72 |
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化学名: |
(S)-Omeprazole potassium salt |
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Solubility (25°C): |
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体外:
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DMSO |
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Ethanol |
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Water |
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体内(现配现用): |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
生物活性
产品描述 |
一种有效的具有口服活性质子泵抑制剂,可通过抑制胃壁细胞中的H+,K+-ATPase来降低酸分泌,并可用于胃食管反流疾病的研究。 |
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靶点 |
H+,K+-ATPase |
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体外研究 |
Esomeprazole (30-300mg/kg;oral gavage;daily;for 19 or 11 days;C57BL/6J mice) treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals. Esomeprazole also reduces circulating markers of inflammation and fibrosis. |
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Cell Line: |
MDA-MB-468 cells |
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Concentration: |
25µM,50µM,75µM,100µM |
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Incubation Time: |
20 hours |
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Result: |
Suppressed growth of triple-negative breast cancer cell in vitro in a dose-dependent manner. |
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体内研究 |
Esomeprazole (30-300mg/kg;oral gavage;daily;for 19 or 11 days;C57BL/6J mice) treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals.Esomeprazole also reduces circulating markers of inflammation and fibrosis. |
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Animal Model: |
C57BL/6J mice (8-weeks old,25-30g) treated with cotton smoke-induced lung injury |
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Dosage: |
30mg/kg,300mg/kg |
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Administration: |
Oral gavage;daily;for 19 or 11 days |
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Result: |
Significantly inhibited the progression of fibrosis throughout the lungs of the animals. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )