基本信息
产品编号: |
D70039 |
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产品名称: |
2,5-Dihydroxybenzoic acid |
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CAS: |
490-79-9 |
储存条件 |
粉末 |
室温 |
四年 |
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分子式: |
溶于液体 |
-80℃ |
6个月 |
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分子量: |
154.12 |
-20℃ |
1个月 |
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化学名: |
2,5-Dihydroxybenzoic acid,matrix substance for MALDI-MS,>=99.5% (HPLC),Ultra pure |
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Solubility (25°C): |
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体外:
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DMSO |
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Ethanol |
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Water |
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体内(现配现用): |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
制备储备液
浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
1mM |
6.4885mL |
32.4423mL |
64.8845mL |
5mM |
1.2977mL |
6.4885mL |
12.9769mL |
10mM |
0.6488mL |
3.2442mL |
6.4885mL |
生物活性
产品描述 |
一种常用的碳水化合物基质。在制药工业上用作抗氧化赋形剂。 |
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靶点 |
Fibroblast growth factor |
Human Endogenous Metabolite |
体外研究 |
2,5-Dihydroxybenzoic acid (Gentisic acid) is a derivative of benzoic and a minor product of the metabolic break down of aspirin.2,5-Dihydroxybenzoic acid is also a component of many traditional liquors and herbal remedies,is singled out as a powerful inhibitor of fibroblast growth factors.2,5-Dihydroxybenzoic acid is used as a lead to identify additional compounds with better inhibitory characteristics generating a new chemical class of fibroblast growth factor inhibitors that includes the agent responsible for alkaptonuria.Through low and high resolution approaches,using representative members of the fibroblast growth factor family and their cell receptors,it is shown that this class of inhibitors may employ two different mechanisms to interfere with the assembly of the signaling complexes that trigger fibroblast growth factor-driven mitogenesis. |
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体内研究 |
It is verified from in vivo disease models that this group of inhibitors (e.g.,2,5-Dihydroxybenzoic acid) may be of interest to treat cancer and angiogenesis-dependent diseases. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )