基本信息
产品编号:D10771 |
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产品名称:7,8-Dihydroneopterin |
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CAS: |
1218-98-0 |
储存条件 |
粉末 |
-20℃ |
四年 |
分子式: |
溶于液体 |
-80℃ |
两年 |
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分子量 |
255.23 |
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化学名: |
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Solubility (25°C) |
体外 |
DMSO |
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Ethanol |
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Water |
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体内(现配现用) |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
生物活性
产品描述 |
一种炎症标记,通过增强一氧化氮合酶 (iNOS) 的表达来诱导星形胶质细胞和神经元细胞凋亡 (apoptosis)。 |
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靶点/IC50 |
Apoptosis; iNOS |
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体外研究 |
7,8-Dihydroneopterin is a heterocyclic pteridine which produced and secreted by monocytes/macrophages upon stimulation with the cytokine interferon-y (IFN-y).7,8-Dihydroneopterin (0.1,0.5,1,2.5,5mM;2 days and 5days) inhibits growth of U373MG astroeytes. Cell Viability Assay |
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Cell Line: |
Astrocytic cell line U373MG |
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Concentration: |
0.1, 0.5, 1, 2.5, 5mM |
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Incubation Time: |
2 days and 5days |
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Result: |
After 2 days of treatment, a significantly lower cell number was observed for those cells treated with 5mM and 2.5mM.After incubation for 5 days concentrations of 1-5mM completely abrogated acid phosphatase activity to background level found for complete cell culture medium.A significant cell growth inhibition was also visible for the cells incubated with 0.5mM,whereas 0.1mM did not alter cell growth. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )