| 中文名称: | CDK2 | ||||
|---|---|---|---|---|---|
| 英文名称: | CDK2 | ||||
| 别名: | His-His-Ala-Ser-Pro-Arg-Lys | ||||
| CAS No: | 255064-79-0 | 分子式: | C35H57N15O9 | 分子量: | 831.92 |
| CAS No: | 255064-79-0 | ||||
| 分子式: | C35H57N15O9 | ||||
| 分子量: | 831.92 | ||||
基本信息
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产品编号： |
C11718 |
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产品名称： |
CDK2 |
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CAS: |
255064-79-0 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式： |
溶于液体 |
-80℃ |
六个月 |
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分子量 |
831.92 |
-20℃ |
一个月 |
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化学名： |
His-His-Ala-Ser-Pro-Arg-Lys |
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生物活性
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产品描述 |
真核S/T蛋白激酶家族的成员,功能是催化 ATPγ 磷酸转移,活性 CDK2 与短肽 (HHASPRK) 底物形成复合物。 |
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体外研究 |
CDK2 (Cyclin-dependent kinase 2) is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. The fully active CDK2 is in complex with HHASPRK (an optimal peptide substrate), namely interactions of CDK2 with peptide substrate and the dynamics of the G-loop. CDK2 participates in eukaryotic cell cycle regulation at the G1/S boundary. CDK2 deregulation has been proved to occur in tumor cells, evoking a strong interest in artificial and native inhibitors. CDK2 activity is tightly regulated by a complex mechanism, including a positive regulatory subunit binding, and phosphorylations at positive and/or negative regulatory sites |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液，使用的计算公式为：
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为：C1V1 = C2V2 ( 输入 输出 )
