中文名称: 3-CPs
英文名称: 3-CPs
CAS No: 20073-24-9
分子式: C14H10O5
分子量: 258.23
C11713 3-CPs ≥95% (psaitong)
包装规格:
1g in glass bottle
产品描述:

基本信息

产品编号:

C11713

产品名称:

3-CPs

CAS:

20073-24-9

 

储存条件

粉末

-20℃

四年

 

 

分子式:

C14H10O5

溶于液体

 

 

分子量

258.23

 

 

化学名: 

3-Carbethoxypsoralen; 3-Ethoxycarbonylpsoralen

 

生物活性

产品描述

可以干扰抗体介导的细菌杀伤的血清型荚膜多糖。

体外研究

3-CPs displays protective effect against UVB damage in all concentrations tested. About 50% inhibition of bacterial killing is observed when 12 ng of purified type 3 CPS is added to the OPKA. The addition of 30μL of mouse serum post-i.p. infection with WU2 (containing 0.4 to 0.7μg/mL released type 3 CPS) shows 26% to 52% inhibition of bacterial killing, comparable to what is observed when an equivalent amount of purified CPS is added

 

推荐实验方法(仅供参考)

Kinase Assay

To measure the inhibitory effect of releaseing type 3-CPs on bacteria killing, an OPKA is performed with the addition of culture supernatant or mouse serum obtained at 24 h following i.p. injection with 103 CFU of the S. pneumoniae WU2 strain. In each well, 10μL of diluted rabbit serum is mixed with 10μL of strain WU2 (1,000 CFU) and 10μL of culture supernatant or mouse serum for 30 min at room temperature before HL-60 cells and complement are added. The percent inhibition of bacterial killing is compared to that with the OPKA with the addition of ΔCPS WU2 culture supernatant or naive mouse serum containing no 3-CPs

保存条件:
-20°C
UN码:
HazardClass:
危害声明:
安全说明:
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