中文名称: | 头孢布烯二水合物 | ||||
---|---|---|---|---|---|
英文名称: | Ceftibuten dihydrate | ||||
别名: | 头孢布坦二水合物;头孢噻腾二水合物 Sch-39720 dihydrate | ||||
CAS No: | 118081-34-8 | 分子式: | C15H18N4O8S2 | 分子量: | 446.46 |
CAS No: | 118081-34-8 | ||||
分子式: | C15H18N4O8S2 | ||||
分子量: | 446.46 |
基本信息
产品编号:C10651 |
|||||
产品名称:Ceftibuten dihydrate |
|||||
CAS: |
118081-34-8 |
储存条件 |
粉末 |
-20℃ |
四年 |
|
|
||||
分子式: |
溶于液体 |
-80℃ |
两年 |
||
分子量 |
446.46 |
-20℃ |
一个月 |
||
化学名: |
|||||
Solubility (25°C) |
体外 |
DMSO |
90mg/mL (201.58mM) |
||
Ethanol |
'-1mg/mL |
||||
Water |
|
||||
体内 |
现配现用 |
|
|||
<1mg/ml表示微溶或不溶。 |
|||||
普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
|||||
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
制备储备液
浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
1mM |
2.2398mL |
11.1992mL |
22.3984mL |
5mM |
0.4480mL |
2.2398mL |
4.4797mL |
10mM |
0.2240mL |
1.1199mL |
2.2398mL |
生物活性
产品描述 |
一种具有口服活性的头孢菌素,在体外对多种革兰氏阴性和某些革兰氏阳性病原体具有较强的抗菌活性。 |
|
靶点/IC50 |
Bacterial |
Antibiotic |
体外研究 |
Ceftibuten (Sch39720) is highly active against Haemophilus influenza, Escherichia coli, Klebsiella sp., and Proteus sp. and moderately active against Serratia sp. and Streptococcus pyogenes. Ceftibuten is relatively inactive against enterococci and staphylococci and is only weakly active against Pseudomonas aeruginosa and obligate anaerobes. It is also stable in the presence of most β-lactamase-producing organisms except βBacteroides fragilis. Ceftibuten is very active against strains of the family Enterobacteriaceae (mean MIC for 90% of strains=0.25μg/ml) but less active against Campylobacterjejuni (mean MIC for 90% of strains=16.0μg/ml). |
|
体内研究 |
Ceftibuten, a biologically stableβ-lactam antibiotic, has been shown to be transported by the small peptide transport system, to have relatively high affinity for the carrier and to show clear stereoselective and proton-gradient dependent transport characteristics in rat intestinal brush-border membrane vesicles. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )