中文名称: | 盐酸贝西沙星 | ||||
---|---|---|---|---|---|
英文名称: | Besifloxacin Hydrochloride | ||||
别名: | 盐酸贝西沙星 Besifloxacin Hydrochloride | ||||
CAS No: | 405165-61-9 | 分子式: | C19H22Cl2FN3O3 | 分子量: | 430.3 |
CAS No: | 405165-61-9 | ||||
分子式: | C19H22Cl2FN3O3 | ||||
分子量: | 430.3 |
包装规格:
100mg in glass bottle
产品简介:
Besifloxacin Hydrochloride 是第四代氟喹诺酮类抗生素。
体外研究:
Besifloxacin是一种新型有效的8-chloro-fluoroquinolone药物,具有对常见病原体和耐药菌的抗菌活性。Besifloxacinis是已经检测的对革兰氏阳性菌和厌氧菌最有效的药物,对大部分革兰氏阴性菌的效果与fluoroquinolones相当。Besifloxacin具有强有效和广谱的抗菌效果尤其值得一提的是对那些其它fluoroquinolones和抗菌药具有抗药性的革兰氏阳性菌和革兰氏阴性菌也有很好的抗菌活性。
激酶实验:
20 ng of purified human DDK, together with increasing
concentrations of each DDK inhibitor is pre-incubated for 5 min. Then 10 μCi (γ)-32P ATP and 1.5 μM cold ATP are added in a buffer containing 50 mM Tris-HCl (pH 7.5), 10 mM MgCl2, and 1 mM DTT and incubated for 30 min at 30°C. The proteins are denatured in 1X Laemmli buffer at 100°C followed by SDS-PAGE and autoradiography on HyBlot CL film. DDK kinase activity is indicated by Auto-phosphorylation of DDK. 32P-labeled bands are quantified using ImageJ and the IC50 values are calculated using GraphPad.
concentrations of each DDK inhibitor is pre-incubated for 5 min. Then 10 μCi (γ)-32P ATP and 1.5 μM cold ATP are added in a buffer containing 50 mM Tris-HCl (pH 7.5), 10 mM MgCl2, and 1 mM DTT and incubated for 30 min at 30°C. The proteins are denatured in 1X Laemmli buffer at 100°C followed by SDS-PAGE and autoradiography on HyBlot CL film. DDK kinase activity is indicated by Auto-phosphorylation of DDK. 32P-labeled bands are quantified using ImageJ and the IC50 values are calculated using GraphPad.
注意事项:
1、为了您的安全和健康,请穿实验服并戴一次性手套操作。
2、以上信息仅做参考交流之用。
2、以上信息仅做参考交流之用。
保存条件:
-20℃
UN码:
HazardClass:
危害声明:
安全说明:
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参考文献 & 客户发表文献
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