中文名称: | β-Amyloid (35-42) | ||||
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英文名称: | β-Amyloid (35-42) | ||||
别名: | β-Amyloid (35-42) Met-Val-Gly-Gly-Val-Val-Ile-Ala | ||||
CAS No: | 183292-41-3 | 分子式: | C33H60N8O9S | 分子量: | 744.94 |
CAS No: | 183292-41-3 | ||||
分子式: | C33H60N8O9S | ||||
分子量: | 744.94 |
基本信息
产品编号: |
A12723 |
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产品名称: |
β-Amyloid (35-42) |
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CAS: |
183292-41-3 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式: |
溶于液体 |
-80℃ |
6个月 |
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分子量 |
744.94 |
-20℃ |
1个月 |
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化学名: |
Met-Val-Gly-Gly-Val-Val-Ile-Ala |
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Solubility (25°C): |
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体外:
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DMSO |
50 mg/mL (67.12mM; Need ultrasonic) |
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Ethanol |
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Water |
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体内(现配现用): |
1.请依序添加每种溶剂:10% DMSO→90% (20% SBE-β-CD in saline) Solubility: 2.5 mg/mL (3.36mM); Suspended solution; Need ultrasonic |
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此⽅案可获得 2.5 mg/mL (3.36mM) 的均匀悬浊液,悬浊液可⽤于⼝服和腹腔注射。 以 1mL ⼯作液为例,取 100μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900μL 20% 的 SBE-β-CD ⽣理盐⽔⽔溶液中,混合均 匀。 |
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2.请依序添加每种溶剂:10% DMSO→90% corn oil Solubility: ≥ 2.5 mg/mL (3.36mM); Clear solution |
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此⽅案可获得 ≥ 2.5 mg/mL (3.36mM,饱和度未知) 的澄清溶液,此⽅案不适⽤于实验周期在半个⽉以上的实验。 以 1mL ⼯作液为例,取 100μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900μL ⽟⽶油中,混合均匀。 |
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<1mg/ml表示微溶或不溶。 |
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普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 |
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;⼀旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
制备储备液
浓度
溶液体积 质量 |
1mg |
5mg |
10mg |
1mM |
1.3424mL |
6.7120mL |
13.4239mL |
5mM |
0.2685mL |
1.3424mL |
2.6848mL |
10mM |
0.1342mL |
0.6712mL |
1.3424mL |
生物活性
产品描述 |
β 淀粉样蛋白的多肽片段,由 35-42 位氨基酸序列组成。 |
靶点 |
Amyloid-β |
体外研究 |
β-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 1. Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure. 2. The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 ℃. 3. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing. 4. Next, the solution was age 48h at 4-8 ℃. The sample was then centrifuged at 14000g for 10 min at 4-8 ℃; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments. Methods vary depends on the downstream applications |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )