中文名称: | β-Amyloid (1-40), FAM-labeled | ||||
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英文名称: | β-Amyloid (1-40), FAM-labeled | ||||
别名: | β-Amyloid (1-40), FAM-labeled | ||||
CAS No: | 1678416-08-4 | 分子式: | C215H305N53O64S | 分子量: | 4688.2 |
CAS No: | 1678416-08-4 | ||||
分子式: | C215H305N53O64S | ||||
分子量: | 4688.2 |
基本信息
产品编号: |
A11831 |
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产品名称: |
β-Amyloid (1-40), FAM-labeled |
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CAS: |
1678416-08-4 |
储存条件 |
粉末 |
-20℃ |
四年 |
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分子式: |
溶于液体 |
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分子量 |
4688.20 |
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化学名: |
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生物活性
产品描述 |
一个 FAM 荧光标记的 β-Amyloid (1-40) 肽 (λex= 492nm and λem= 518nm)。 |
靶点 |
λex= 492nm; λem= 518nm |
体外研究 |
Apical-to-basolateral exchange across endothelial monolayer of fluorescent Aβ42 (FAM-labeled Human β-Amyloid (1-42) and Fluor™488-labeled β-Amyloid (1-42)) or scramble Aβ42 (FAM-labeled scrambled β-Amyloid (1-42)) (1-100μM) is monitored in transendothelial electrical resistance (TEER) during cell monolayer’s formation over time (over 120 min in presence or absence of Aβ24). Human β-Amyloid (1-24) (1μM) results in H-Aβ42 retention, thus reducing its efflux through the BBB and therefore preventing an efficient mechanism of Aβ42 clearance[1] . The in vitro BBB model is used to investigate the passage of FAM-labeled or 488-conjugated H-Aβ42 across the endothelial cell monolayer. The addition of fluorescently labeled H-Aβ42 (FAM-labeled Human β-Amyloid (1-42) or Fluor™ 488-labeled βAmyloid (1-42)) to the apical side of cell inserts results in effective BBB crossing, FAM-labeled scrambled β-Amyloid (1-42) is not efficiently transcytosed. |
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)
摩尔浓度计算公式
用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积
稀释公式
稀释公式一般简略地表示为:C1V1 = C2V2 ( 输入 输出 )