中文名称: β-Amyloid (1-40), FAM-labeled
英文名称: β-Amyloid (1-40), FAM-labeled
CAS No: 1678416-08-4
分子式: C215H305N53O64S
分子量: 4688.2
A11831 β-Amyloid (1-40), FAM-labeled ≥95% (psaitong)
包装规格:
1mg 5mg in glass bottle
产品描述:

基本信息

产品编号:

A11831

产品名称:

β-Amyloid (1-40), FAM-labeled

CAS:

1678416-08-4

 

储存条件

粉末

-20℃

四年

 

 

分子式:

C215H305N53O64S

溶于液体

 

 

分子量

4688.20

 

 

化学名: 

 

 

生物活性

产品描述

一个 FAM 荧光标记的 β-Amyloid (1-40) 肽 (λex= 492nm and λem= 518nm)。

靶点

λex= 492nm; λem= 518nm

体外研究

Apical-to-basolateral exchange across endothelial monolayer of fluorescent Aβ42 (FAM-labeled Human β-Amyloid (1-42) and Fluor™488-labeled β-Amyloid (1-42)) or scramble Aβ42 (FAM-labeled scrambled β-Amyloid (1-42)) (1-100μM) is monitored in transendothelial electrical resistance (TEER) during cell monolayer’s formation over time (over 120 min in presence or absence of Aβ24). Human β-Amyloid (1-24) (1μM) results in H-Aβ42 retention, thus reducing its efflux through the BBB and therefore preventing an efficient mechanism of Aβ42 clearance[1] . The in vitro BBB model is used to investigate the passage of FAM-labeled or 488-conjugated H-Aβ42 across the endothelial cell monolayer. The addition of fluorescently labeled H-Aβ42 (FAM-labeled Human β-Amyloid (1-42) or Fluor™ 488-labeled βAmyloid (1-42)) to the apical side of cell inserts results in effective BBB crossing, FAM-labeled scrambled β-Amyloid (1-42) is not efficiently transcytosed.

保存条件:
-20°C
UN码:
HazardClass:
危害声明:
安全说明:
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参考文献 & 客户发表文献

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

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用本工具协助配置特定浓度的溶液,使用的计算公式为:
开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

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  • 稀释倍数:
  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):