2020-10-21

1: Zhao Q, Li M, Chen M, Zhou L, Zhao L, Hu R, Yan R, Dai K. Lovastatin induces 
platelet apoptosis. Environ Toxicol Pharmacol. 2016 Mar;42:69-75. doi: 
10.1016/j.etap.2016.01.002. Epub 2016 Jan 4. PubMed PMID: 26773364.

2: Zhao N, Dong Q, Qian C, Li S, Wu QF, Ding D, Li J, Wang BB, Guo KF, Xie JJ, 
Cheng X, Liao YH, Du YM. Corrigendum: Lovastatin blocks Kv1.3 channel in human T 
cells: a new mechanism to explain its immunomodulatory properties. Sci Rep. 2016 
Mar 10;6:21655. doi: 10.1038/srep21655. PubMed PMID: 26961979; PubMed Central 
PMCID: PMC4785556.

3: Walther U, Emmrich K, Ramer R, Mittag N, Hinz B. Lovastatin lactone elicits 
human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway. Oncotarget. 
2016 Feb 5. doi: 10.18632/oncotarget.7213. [Epub ahead of print] PubMed PMID: 
26863638.

4: Krüger K, Ziegler V, Hartmann C, Henninger C, Thomale J, Schupp N, Fritz G. 
Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage 
response (DDR) of renal tubular epithelial cells. Toxicol Appl Pharmacol. 2016 
Feb 1;292:103-14. doi: 10.1016/j.taap.2015.12.023. Epub 2015 Dec 29. PubMed PMID: 
26739623.

5: Lin CH, Lin HI, Chen ML, Lai TT, Cao LP, Farrer MJ, Wu RM, Chien CT. 
Lovastatin protects neurite degeneration in LRRK2-G2019S parkinsonism through 
activating the Akt/Nrf pathway and inhibiting GSK3β activity. Hum Mol Genet. 2016 
Feb 29. pii: ddw068. [Epub ahead of print] PubMed PMID: 26931464.

6: Ziegler V, Albers A, Fritz G. Lovastatin protects keratinocytes from DNA 
damage-related pro-apoptotic stress responses stimulated by anticancer 
therapeutics. Biochim Biophys Acta. 2016 Feb 12. pii: S0167-4889(16)30025-8. doi: 
10.1016/j.bbamcr.2016.02.009. [Epub ahead of print] PubMed PMID: 26876155.

7: Riekes MK, Engelen A, Appeltans B, Rombaut P, Stulzer HK, Van den Mooter G. 
New Perspectives for Fixed Dose Combinations of Poorly Water-Soluble Compounds: a 
Case Study with Ezetimibe and Lovastatin. Pharm Res. 2016 Feb 8. [Epub ahead of 
print] PubMed PMID: 26857899.

8: Whitehorn J, Nguyen CV, Khanh LP, Kien DT, Quyen NT, Tran NT, Hang NT, Truong 
NT, Hue Tai LT, Cam Huong NT, Nhon VT, Van Tram T, Farrar J, Wolbers M, Simmons 
CP, Wills B. Lovastatin for the Treatment of Adult Patients With Dengue: A 
Randomized, Double-Blind, Placebo-Controlled Trial. Clin Infect Dis. 2016 Feb 
15;62(4):468-76. doi: 10.1093/cid/civ949. Epub 2015 Nov 12. PubMed PMID: 
26565005; PubMed Central PMCID: PMC4725386.

9: Yang SH, Lin HY, Changou CA, Chen CH, Liu YR, Wang J, Jiang X, Luh F, Yen Y. 
Integrin β3 and LKB1 are independently involved in the inhibition of 
proliferation by lovastatin in human intrahepatic cholangiocarcinoma. Oncotarget. 
2016 Jan 5;7(1):362-73. doi: 10.18632/oncotarget.6238. PubMed PMID: 26517522.

10: Lee BS, Lee CC, Wang YP, Chen HJ, Lai CH, Hsieh WL, Chen YW. 
Controlled-release of tetracycline and lovastatin by 
poly(d,l-lactide-co-glycolide acid)-chitosan nanoparticles enhances periodontal 
regeneration in dogs. Int J Nanomedicine. 2016 Jan 18;11:285-97. doi: 
10.2147/IJN.S94270. eCollection 2016. PubMed PMID: 26848264; PubMed Central 
PMCID: PMC4723100.

11: Yang T, Yao H, He G, Song L, Liu N, Wang Y, Yang Y, Keller ET, Deng X. 
Effects of Lovastatin on MDA-MB-231 Breast Cancer Cells: An Antibody Microarray 
Analysis. J Cancer. 2016 Jan 1;7(2):192-9. doi: 10.7150/jca.13414. eCollection 
2016. PubMed PMID: 26819643; PubMed Central PMCID: PMC4716852.

12: Cacho RA, Thuss J, Xu W, Sanichar R, Gao Z, Nguyen A, Vederas JC, Tang Y. 
Understanding Programming of Fungal Iterative Polyketide Synthases: The 
Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the 
Lovastatin Megasynthase. J Am Chem Soc. 2015 Dec 23;137(50):15688-91. doi: 
10.1021/jacs.5b11814. Epub 2015 Dec 10. PubMed PMID: 26630357.

13: Chen CC, Liu TY, Huang SP, Ho CT, Huang TC. Differentiation and apoptosis 
induction by lovastatin and γ-tocotrienol in HL-60 cells via Ras/ERK/NF-κB and 
Ras/Akt/NF-κB signaling dependent down-regulation of glyoxalase 1 and HMG-CoA 
reductase. Cell Signal. 2015 Nov;27(11):2182-90. doi: 
10.1016/j.cellsig.2015.07.014. Epub 2015 Jul 21. PubMed PMID: 26208883.

14: Chen CB, Chen J, Wang J, Zhu YY, Shi JH. Combined spectroscopic and molecular 
docking approach to probing binding interactions between lovastatin and calf 
thymus DNA. Luminescence. 2015 Nov;30(7):1004-10. doi: 10.1002/bio.2851. Epub 
2015 Feb 1. PubMed PMID: 25640921.

15: Zhao N, Dong Q, Qian C, Li S, Wu QF, Ding D, Li J, Wang BB, Guo KF, Xie JJ, 
Cheng X, Liao YH, Du YM. Lovastatin blocks Kv1.3 channel in human T cells: a new 
mechanism to explain its immunomodulatory properties. Sci Rep. 2015 Nov 
30;5:17381. doi: 10.1038/srep17381. PubMed PMID: 26616555; PubMed Central PMCID: 
PMC4663632.

16: Mulder KC, Mulinari F, Franco OL, Soares MS, Magalhães BS, Parachin NS. 
Lovastatin production: From molecular basis to industrial process optimization. 
Biotechnol Adv. 2015 Nov 1;33(6 Pt 1):648-65. doi: 
10.1016/j.biotechadv.2015.04.001. Epub 2015 Apr 11. Review. PubMed PMID: 
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17: Dikshit R, Tallapragada P. Bio-synthesis and screening of nutrients for 
lovastatin by Monascus sp. under solid-state fermentation. J Food Sci Technol. 
2015 Oct;52(10):6679-86. doi: 10.1007/s13197-014-1678-y. Epub 2015 Feb 11. PubMed 
PMID: 26396416; PubMed Central PMCID: PMC4573169.

18: Guimarães MR, Murad LB, Paganelli A, de Oliveira CA, Vianna LM. Effects of 
alpha-tocopherol associated with lovastatin on brain tissue and memory function 
in SHRSPs. Physiol Behav. 2015 Oct 1;149:303-9. doi: 
10.1016/j.physbeh.2015.06.025. Epub 2015 Jun 19. PubMed PMID: 26095118.

19: He H, Zhang M, Liu L, Zhang S, Liu J, Zhang W. Suppression of Remodeling 
Behaviors with Arachidonic Acid Modification for Enhanced in vivo Antiatherogenic 
Efficacies of Lovastatin-loaded Discoidal Recombinant High Density Lipoprotein. 
Pharm Res. 2015 Oct;32(10):3415-31. doi: 10.1007/s11095-015-1719-x. Epub 2015 Jun 
4. PubMed PMID: 26040661.

20: Kuzma-Kuzniarska M, Cornell HR, Moneke MC, Carr AJ, Hulley PA. 
Lovastatin-Mediated Changes in Human Tendon Cells. J Cell Physiol. 2015 
Oct;230(10):2543-51. doi: 10.1002/jcp.25010. PubMed PMID: 25846724.