2020-10-20

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2: Parajuli SP, Hristov KL, Soder RP, Kellett WF, Petkov GV. NS309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels. Br J Pharmacol. 2013 Apr;168(7):1611-25. doi: 10.1111/bph.12049. PubMed PMID: 23145946; PubMed Central PMCID: PMC3605870.

3: Kroigaard C, Dalsgaard T, Nielsen G, Laursen BE, Pilegaard H, Köhler R, Simonsen U. Activation of endothelial and epithelial K(Ca) 2.3 calcium-activated potassium channels by NS309 relaxes human small pulmonary arteries and bronchioles. Br J Pharmacol. 2012 Sep;167(1):37-47. doi: 10.1111/j.1476-5381.2012.01986.x. PubMed PMID: 22506557; PubMed Central PMCID: PMC3448912.

4: Seear RV, Lew VL. IKCa agonist (NS309)-elicited all-or-none dehydration response of human red blood cells is cell-age dependent. Cell Calcium. 2011 Nov;50(5):444-8. doi: 10.1016/j.ceca.2011.07.005. Epub 2011 Sep 21. PubMed PMID: 21937109.

5: Brøndum E, Kold-Petersen H, Simonsen U, Aalkjaer C. NS309 restores EDHF-type relaxation in mesenteric small arteries from type 2 diabetic ZDF rats. Br J Pharmacol. 2010 Jan;159(1):154-65. doi: 10.1111/j.1476-5381.2009.00525.x. Epub 2009 Dec 10. PubMed PMID: 20015296; PubMed Central PMCID: PMC2823361.

6: Pandita RK, Rønn LC, Jensen BS, Andersson KE. Urodynamic effects of intravesical administration of the new small/intermediate conductance calcium activated potassium channel activator NS309 in freely moving, conscious rats. J Urol. 2006 Sep;176(3):1220-4. PubMed PMID: 16890729.

7: Strøbaek D, Teuber L, Jørgensen TD, Ahring PK, Kjaer K, Hansen RS, Olesen SP, Christophersen P, Skaaning-Jensen B. Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime). Biochim Biophys Acta. 2004 Oct 11;1665(1-2):1-5. PubMed PMID: 15471565.