2020-10-20

1: Teema AM, Zaitone SA, Moustafa YM. Ibuprofen or piroxicam protects nigral 
neurons and delays the development of L-dopa induced dyskinesia in rats with 
experimental Parkinsonism: influence on angiogenesis. Neuropharmacology. 2016 Mar 
22. pii: S0028-3908(16)30106-X. doi: 10.1016/j.neuropharm.2016.03.034. [Epub 
ahead of print] PubMed PMID: 27016022.

2: Penkina A, Semjonov K, Hakola M, Vuorinen S, Repo T, Yliruusi J, Aruväli J, 
Kogermann K, Veski P, Heinämäki J. Towards improved solubility of poorly 
water-soluble drugs: cryogenic co-grinding of piroxicam with carrier polymers. 
Drug Dev Ind Pharm. 2016 Mar;42(3):378-88. doi: 10.3109/03639045.2015.1054400. 
Epub 2015 Jun 11. PubMed PMID: 26065533.

3: Garg V, Singh H, Bhatia A, Raza K, Singh SK, Singh B, Beg S. Systematic 
Development of Transethosomal Gel System of Piroxicam: Formulation Optimization, 
In Vitro Evaluation, and Ex Vivo Assessment. AAPS PharmSciTech. 2016 Feb 11. 
[Epub ahead of print] PubMed PMID: 26868380.

4: Calvo AM, Santos GM, Dionísio TJ, Marques MP, Brozoski DT, Lanchote VL, 
Fernandes MH, Faria FA, Santos CF. Quantification of piroxicam and 
5'-hydroxypiroxicam in human plasma and saliva using liquid chromatography-tandem 
mass spectrometry following oral administration. J Pharm Biomed Anal. 2016 Feb 
20;120:212-20. doi: 10.1016/j.jpba.2015.12.042. Epub 2015 Dec 28. PubMed PMID: 
26760238.

5: Sahu CR. Mechanisms Involved in Toxicity of Liver Caused by Piroxicam in Mice 
and Protective Effects of Leaf Extract of Hibiscus rosa-sinensis L. Clin Med 
Insights Arthritis Musculoskelet Disord. 2016 Jan 19;9:9-13. doi: 
10.4137/CMAMD.S29463. eCollection 2016. PubMed PMID: 26819562; PubMed Central 
PMCID: PMC4720181.

6: Sivaraman A, Banga AK. Formulation and evaluation of sublingual delivery of 
piroxicam using thermosensitive polymer with an inverted Franz diffusion cell. J 
Pharm Pharmacol. 2016 Jan;68(1):26-35. doi: 10.1111/jphp.12493. Epub 2015 Dec 29. 
PubMed PMID: 26714423.

7: Rai N, Sarkar M, Raha S. Piroxicam, a traditional non-steroidal 
anti-inflammatory drug (NSAID) causes apoptosis by ROS mediated Akt activation. 
Pharmacol Rep. 2015 Dec;67(6):1215-23. doi: 10.1016/j.pharep.2015.05.012. Epub 
2015 May 30. PubMed PMID: 26481545.

8: Choisunirachon N, Jaroensong T, Yoshida K, Saeki K, Mochizuki M, Nishimura R, 
Sasaki N, Nakagawa T. Effects of low-dose cyclophosphamide with piroxicam on 
tumour neovascularization in a canine oral malignant melanoma-xenografted mouse 
model. Vet Comp Oncol. 2015 Dec;13(4):424-32. doi: 10.1111/vco.12059. Epub 2013 
Jul 26. PubMed PMID: 23890026.

9: Maciá Martínez MÁ. Economic evaluation of the restriction in the use piroxicam 
in Spain. Reumatol Clin. 2015 Nov-Dec;11(6):345-352. doi: 
10.1016/j.reuma.2014.12.003. Epub 2015 Jan 28. English, Spanish. PubMed PMID: 
25636384.

10: Farooq A, Yar M, Khan AS, Shahzadi L, Siddiqi SA, Mahmood N, Rauf A, Qureshi 
ZU, Manzoor F, Chaudhry AA, ur Rehman I. Synthesis of piroxicam loaded novel 
electrospun biodegradable nanocomposite scaffolds for periodontal regeneration. 
Mater Sci Eng C Mater Biol Appl. 2015 Nov 1;56:104-13. doi: 
10.1016/j.msec.2015.06.006. Epub 2015 Jun 14. PubMed PMID: 26249571.

11: Bhattacharya P, Pandey AK, Paul S, Patnaik R. Piroxicam-mediated modulatory 
action of 5-hydroxytryptamine serves as a "brake" on neuronal excitability in 
ischemic stroke. Neural Regen Res. 2015 Sep;10(9):1418-20. doi: 
10.4103/1673-5374.165509. PubMed PMID: 26604901; PubMed Central PMCID: 
PMC4625506.

12: John P, Azeem W, Ashfaq M, Khan IU, Razzaq SN. Stability indicating RP-HPLC 
method for simultaneous determination of piroxicam and ofloxacin in binary 
combination. Pak J Pharm Sci. 2015 Sep;28(5):1713-21. PubMed PMID: 26408892.

13: Santiago RM, Tonin FS, Barbiero J, Zaminelli T, Boschen SL, Andreatini R, Da 
Cunha C, Lima MM, Vital MA. The nonsteroidal antiinflammatory drug piroxicam 
reverses the onset of depressive-like behavior in 6-OHDA animal model of 
Parkinson's disease. Neuroscience. 2015 Aug 6;300:246-53. doi: 
10.1016/j.neuroscience.2015.05.030. Epub 2015 May 18. PubMed PMID: 25999296.

14: Lavrič Z, Pirnat J, Lužnik J, Puc U, Trontelj Z, Srčič S. (14) N nuclear 
quadrupole resonance study of piroxicam: confirmation of new polymorphic form V. 
J Pharm Sci. 2015 Jun;104(6):1909-18. doi: 10.1002/jps.24421. Epub 2015 Mar 16. 
PubMed PMID: 25776345.

15: Astani A, Albrecht U, Schnitzler P. Piroxicam inhibits herpes simplex virus 
type 1 infection in vitro. Pharmazie. 2015 May;70(5):331-6. PubMed PMID: 
26062303.

16: Hasegawa Y, Higashi K, Yamamoto K, Moribe K. Direct evaluation of molecular 
States of piroxicam/poloxamer nanosuspension by suspended-state NMR and Raman 
spectroscopies. Mol Pharm. 2015 May 4;12(5):1564-72. doi: 10.1021/mp500872g. Epub 
2015 Apr 17. PubMed PMID: 25849345.

17: KandaSwamy GV, Dhanasekaran AK, Elangovan A, John B, Viswaroop B, Vedanayagam 
KS. Randomized double blinded placebo controlled trial comparing diclofenac and 
piroxicam in management of acute renal colic and its clinical implications. Urol 
J. 2015 Apr 29;12(2):2069-73. PubMed PMID: 25923150.

18: Suresh S, Gunasekaran S, Srinivasan S. Vibrational spectra (FT-IR, FT-Raman), 
frontier molecular orbital, first hyperpolarizability, NBO analysis and 
thermodynamics properties of Piroxicam by HF and DFT methods. Spectrochim Acta A 
Mol Biomol Spectrosc. 2015 Mar 5;138:447-59. doi: 10.1016/j.saa.2014.11.040. Epub 
2014 Nov 28. PubMed PMID: 25523048.

19: Singh AK, Pathak K. Colon specific CODES based Piroxicam tablet for colon 
targeting: statistical optimization, in vivo roentgenography and stability 
assessment. Pharm Dev Technol. 2015 Mar;20(2):237-45. doi: 
10.3109/10837450.2013.860549. Epub 2013 Nov 25. PubMed PMID: 24266719.

20: Holgersen K, Dobie R, Farquharson C, vanʼt Hof R, Ahmed SF, Hansen AK, Holm 
TL. Piroxicam treatment augments bone abnormalities in interleukin-10 knockout 
mice. Inflamm Bowel Dis. 2015 Feb;21(2):257-66. doi: 
10.1097/MIB.0000000000000269. PubMed PMID: 25569742.