2020-10-20

1: Zhou Y, Guo F. A selective sphingosine-1-phosphate receptor 1 agonist SEW-2871 aggravates gastric cancer by recruiting myeloid-derived suppressor cells. J Biochem. 2017 Oct 3. doi: 10.1093/jb/mvx064. [Epub ahead of print] PubMed PMID: 29036438.

2: Mohamed AS, Hanafi NI, Sheikh Abdul Kadir SH, Md Noor J, Abdul Hamid Hasani N, Ab Rahim S, Siran R. Ursodeoxycholic acid protects cardiomyocytes against cobalt

chloride induced hypoxia by regulating transcriptional mediator of cells stress hypoxia inducible factor 1α and p53 protein. Cell Biochem Funct. 2017 Oct 12. doi: 10.1002/cbf.3303. [Epub ahead of print] PubMed PMID: 29027248.

3: Werth S, Müller-Fielitz H, Raasch W. Obesity-stimulated aldosterone release is not related to a S1P-dependent mechanism. J Endocrinol. 2017 Oct 2. pii: JOE-16-0550. doi: 10.1530/JOE-16-0550. [Epub ahead of print] PubMed PMID: 28970286.

4: Blanco R, Martínez-Navarrete G, Valiente-Soriano FJ, Avilés-Trigueros M, Pérez-Rico C, Serrano-Puebla A, Boya P, Fernández E, Vidal-Sanz M, de la Villa P. The S1P1 receptor-selective agonist CYM-5442 protects retinal ganglion cells in endothelin-1 induced retinal ganglion cell loss. Exp Eye Res. 2017 Nov;164:37-45. doi: 10.1016/j.exer.2017.08.005. Epub 2017 Aug 4. PubMed PMID: 28827028.

5: Sun X, Mathew B, Sammani S, Jacobson JR, Garcia JGN. Simvastatin-induced sphingosine 1-phosphate receptor 1 expression is KLF2-dependent in human lung endothelial cells. Pulm Circ. 2017 Mar 21;7(1):117-125. doi: 10.1177/2045893217701162. eCollection 2017 Mar. PubMed PMID: 28680571; PubMed Central PMCID: PMC5448536.

6: Onuma T, Tanabe K, Kito Y, Tsujimoto M, Uematsu K, Enomoto Y, Matsushima-Nishiwaki R, Doi T, Nagase K, Akamatsu S, Tokuda H, Ogura S, Iwama T,

Kozawa O, Iida H. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. Thromb Res. 2017 Aug;156:91-100. doi: 10.1016/j.thromres.2017.06.001. Epub 2017 Jun 2. PubMed PMID: 28609704.

7: Ahmed N, Linardi D, Decimo I, Mehboob R, Gebrie MA, Innamorati G, Luciani GB,

Faggian G, Rungatscher A. Characterization and Expression of Sphingosine 1-Phosphate Receptors in Human and Rat Heart. Front Pharmacol. 2017 May 24;8:312. doi: 10.3389/fphar.2017.00312. eCollection 2017. PubMed PMID: 28596734; PubMed Central PMCID: PMC5442178.

8: Flemming S, Burkard N, Meir M, Schick MA, Germer CT, Schlegel N. Sphingosine-1-phosphate Receptor-1 Agonist SEW2871 Causes Severe Cardiac Side Effects and does not Improve Microvascular Barrier Breakdown in Sepsis. Shock. 2017 May 23. doi: 10.1097/SHK.0000000000000908. [Epub ahead of print] PubMed PMID: 28538086.

9: Meshcheryakova A, Mechtcheriakova D, Pietschmann P. Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential. Expert Opin Ther Targets. 2017 Jul;21(7):725-737. doi: 10.1080/14728222.2017.1332180. Epub 2017 Jun 7. Review. PubMed PMID: 28524744; PubMed Central PMCID: PMC5470107.

10: Troupiotis-Tsaïlaki A, Zachmann J, González-Gil I, Gonzalez A, Ortega-Gutiérrez S, López-Rodríguez ML, Pardo L, Govaerts C. Ligand chain length

drives activation of lipid G protein-coupled receptors. Sci Rep. 2017 May 17;7(1):2020. doi: 10.1038/s41598-017-02104-5. PubMed PMID: 28515494; PubMed Central PMCID: PMC5435731.

11: Jiang H, Shen SM, Yin J, Zhang PP, Shi Y. Sphingosine 1-phosphate receptor 1

(S1PR1) agonist CYM5442 inhibits expression of intracellular adhesion molecule 1

(ICAM1) in endothelial cells infected with influenza A viruses. PLoS One. 2017 Apr 11;12(4):e0175188. doi: 10.1371/journal.pone.0175188. eCollection 2017. PubMed PMID: 28399143; PubMed Central PMCID: PMC5388330.

12: Caliman AD, Miao Y, McCammon JA. Activation mechanisms of the first sphingosine-1-phosphate receptor. Protein Sci. 2017 Jun;26(6):1150-1160. doi: 10.1002/pro.3165. Epub 2017 Apr 12. PubMed PMID: 28370663; PubMed Central PMCID:

PMC5441409.

13: James E, Pertusati F, Brancale A, McGuigan C. Kinase-independent phosphoramidate S1P(1) receptor agonist benzyl ether derivatives. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1371-1378. doi: 10.1016/j.bmcl.2017.02.011. Epub 2017 Feb 9. PubMed PMID: 28236593.

14: Schnute ME, McReynolds MD, Carroll J, Chrencik J, Highkin MK, Iyanar K, Jerome G, Rains JW, Saabye M, Scholten JA, Yates M, Nagiec MM. Discovery of a Potent and Selective Sphingosine Kinase 1 Inhibitor through the Molecular Combination of Chemotype-Distinct Screening Hits. J Med Chem. 2017 Mar 23;60(6):2562-2572. doi: 10.1021/acs.jmedchem.7b00070. Epub 2017 Mar 6. PubMed PMID: 28231433.

15: Bettiga A, Aureli M, Colciago G, Murdica V, Moschini M, Lucianò R, Canals D,

Hannun Y, Hedlund P, Lavorgna G, Colombo R, Bassi R, Samarani M, Montorsi F, Salonia A, Benigni F. Bladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism. Sci Rep. 2017 Feb 13;7:42157. doi: 10.1038/srep42157. PubMed PMID: 28191815; PubMed Central PMCID: PMC5304189.

16: Green CL, Mitchell SE, Derous D, Wang Y, Chen L, Han JJ, Promislow DEL, Lusseau D, Douglas A, Speakman JR. The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice. Aging Cell. 2017 Jun;16(3):529-540. doi: 10.1111/acel.12570. Epub 2017 Jan 31. PubMed PMID: 28139067; PubMed Central PMCID: PMC5418186.

17: Giles C, Takechi R, Mellett NA, Meikle PJ, Dhaliwal S, Mamo JC. Differential

regulation of sphingolipid metabolism in plasma, hippocampus, and cerebral cortex of mice administered sphingolipid modulating agents. J Neurochem. 2017 May;141(3):413-422. doi: 10.1111/jnc.13964. Epub 2017 Feb 28. PubMed PMID: 28129448.

18: Mi J, Zhao M, Yang S, Jia Y, Wang Y, Wang B, Jin J, Wang X, Xiao Q, Hu J, Li

Y. Identification of cytochrome P450 isoforms involved in the metabolism of Syl930, a selective S1PR(1) agonist acting as a potential therapeutic agent for autoimmune encephalitis. Drug Metab Pharmacokinet. 2017 Feb;32(1):53-60. doi: 10.1016/j.dmpk.2016.07.002. Epub 2016 Jul 14. PubMed PMID: 28126315.

19: St-Cyr Giguère F, Attiori Essis S, Chagniel L, Germain M, Cyr M, Massicotte G. The sphingosine-1-phosphate receptor 1 agonist SEW2871 reduces Tau-Ser262 phosphorylation in rat hippocampal slices. Brain Res. 2017 Mar 1;1658:51-59. doi: 10.1016/j.brainres.2017.01.014. Epub 2017 Jan 16. PubMed PMID: 28104351.

20: Meissner A, Miro F, Jiménez-Altayó F, Jurado A, Vila E, Planas AM. Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension. Cardiovasc Res. 2017 Feb;113(2):123-133. doi: 10.1093/cvr/cvw256. Epub 2017 Jan 12. PubMed PMID: 28082452.